Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.33 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.31 |
| ▸ | LSS | P48449 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18624578 | 1.00 | HSD11B1 (0.40) | HSD11B1ASGR1KDM4DLSSPDE10A | |
| SCHEMBL190837 | 0.86 | HSD11B1 (0.47) | HSD11B1ASGR1KDM4DPDE10A | |
| SCHEMBL562998 | 0.84 | HSD11B1 (0.40) | HSD11B1ASGR1KDM4D | |
| SCHEMBL4804660 | 0.82 | LSS (0.39) | HSD11B1ASGR1LSS | |
| SCHEMBL4804655 | 0.82 | LSS (0.39) | HSD11B1ASGR1LSS | |
| SCHEMBL28804055 | 0.81 | HSD11B1 (0.44) | HSD11B1ASGR1KDM4DPDE10A | |
| SCHEMBL28804053 | 0.81 | HSD11B1 (0.44) | HSD11B1ASGR1KDM4DPDE10A | |
| SCHEMBL228179 | 0.81 | HSD11B1 (0.46) | HSD11B1ASGR1KDM4DPDE10A | |
| SCHEMBL1344888 | 0.80 | HSD11B1 (0.41) | HSD11B1ASGR1KDM4D | |
| SCHEMBL1299111 | 0.80 | HSD11B1 (0.41) | HSD11B1ASGR1KDM4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3929199-A1 | NOVEL HETEROTRICYCLIC DERIVATIVE COMPOUND AND USE OF SAME | Hanmi Pharmaceutical Co., Ltd. (KR) | 2021-12-29 | — | — | EP | disclosed |
| CN-106132954-B | 1,3- benzodioxole derivative | 第三共株式会社 | 2019-01-08 | — | — | CN | disclosed |