SCHEMBL2414580

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL620721	0.86	ABCB1 (0.53)	NPC1RAB9AMAOBABCB1HTR1A
	SCHEMBL621853	0.84	NPC1 (0.51)	NPC1RAB9AMAOBHTR1AALDH1A1
	SCHEMBL188646	0.83	NPC1 (0.59)	NPC1RAB9AMAOBABCB1HTR1A
	SCHEMBL7978920	0.81	NPC1 (0.61)	NPC1RAB9AMAOBABCB1HTR1A
	SCHEMBL12358221	0.81	NPC1 (0.65)	NPC1RAB9AMAOBABCB1HTR1A
	SCHEMBL621074	0.79	NPC1 (0.50)	NPC1RAB9AABCB1HTR1AADRA1D
	SCHEMBL2420234	0.78	NPC1 (0.53)	NPC1RAB9AABCB1HTR1AADRA1D
	SCHEMBL621125	0.78	NPC1 (0.50)	NPC1RAB9AMAOBABCB1HTR1A
	SCHEMBL1154799	0.77	CD274 (0.43)	NPC1RAB9AMAOBMAPTSMN1; SMN2
	SCHEMBL621208	0.77	DCPS (0.46)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.