SCHEMBL24147281

SCHEMBL24147281

CCCOc1ccc(Cc2cc(C3(OC)CC(O)[C@H](O)C(CO)O3)ccc2Cl)cc1

nearest known ligand 0.51

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 20/20 0.51
SLC5A1 P13866 8/20 0.49
ADRA2A P08913 1/20 0.46
SLC5A11 Q8WWX8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23453206 0.93 SLC5A2 (0.59) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL19676633 0.93 SLC5A2 (0.59) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL19676719 0.93 SLC5A2 (0.59) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL19215280 0.90 SLC5A2 (0.60) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL10210912 0.90 SLC5A2 (0.60) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL27913 0.87 SLC5A2 (0.51) SLC5A2SLC5A1
SCHEMBL28693 0.87 SLC5A2 (0.47) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL27889 0.87 SLC5A2 (0.47) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL26903 0.87 SLC5A2 (0.47) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL29512 0.86 SLC5A2 (0.46) SLC5A2SLC5A1ADRA2ASLC5A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021260617-A1 AN IMPROVED PROCESS FOR PREPARATION OF DAPAGLIFLOZIN PROPANEDIOL MONOHYDRATE HIKAL LIMITED (IN) 2021-12-30 WO disclosed