SCHEMBL27913

SCHEMBL27913

CCC1(COc2ccc(Cc3cc([C@@]4(OC)C[C@@H](O)[C@H](O)[C@@H](CO)O4)ccc3Cl)cc2)COC1

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 20/20 0.51
SLC5A1 P13866 11/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27889 0.92 SLC5A2 (0.47) SLC5A2SLC5A1
SCHEMBL26903 0.92 SLC5A2 (0.47) SLC5A2SLC5A1
SCHEMBL28693 0.92 SLC5A2 (0.47) SLC5A2SLC5A1
SCHEMBL29512 0.91 SLC5A2 (0.46) SLC5A2SLC5A1
SCHEMBL23453206 0.88 SLC5A2 (0.59) SLC5A2SLC5A1
SCHEMBL19676719 0.88 SLC5A2 (0.59) SLC5A2SLC5A1
SCHEMBL19676633 0.88 SLC5A2 (0.59) SLC5A2SLC5A1
SCHEMBL18146 0.88 SLC5A2 (0.55) SLC5A2SLC5A1
SCHEMBL24147281 0.87 SLC5A2 (0.51) SLC5A2SLC5A1
SCHEMBL10210912 0.82 SLC5A2 (0.60) SLC5A2SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012025857-A1 CYCLOALKYL METHOXYBENZYL PHENYL PYRAN DERIVATIVES AS SODIUM DEPENDENT GLUCOSE CO TRANSPORTER (SGLT2) INHIBITORS HETERO RESEARCH FOUNDATION (IN) 2012-03-01 WO disclosed