Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 20/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.78 |
| ▸ | TTK | P33981 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24146920 | 1.00 | LRRK2 (0.78) | LRRK2CYP1A2TTK | |
| SCHEMBL24147024 | 1.00 | LRRK2 (0.78) | LRRK2CYP1A2TTK | |
| SCHEMBL16469355 | 0.92 | LRRK2 (0.78) | LRRK2CYP1A2TTK | |
| SCHEMBL24147267 | 0.90 | LRRK2 (0.65) | LRRK2CYP1A2TTK | |
| SCHEMBL24147457 | 0.90 | LRRK2 (0.65) | LRRK2CYP1A2TTK | |
| SCHEMBL24146954 | 0.90 | LRRK2 (0.65) | LRRK2CYP1A2TTK | |
| SCHEMBL24147251 | 0.88 | LRRK2 (0.60) | LRRK2CYP1A2TTK | |
| SCHEMBL24146928 | 0.88 | LRRK2 (0.60) | LRRK2CYP1A2TTK | |
| SCHEMBL24147264 | 0.88 | LRRK2 (0.60) | LRRK2CYP1A2TTK | |
| Dnl-201 SCHEMBL4561063 | 0.88 | LRRK2 (1.00) | LRRK2CYP1A2TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220119371-A1 | COMPOUND, COMPOSITIONS, AND METHODS | DENALI THERAPEUTICS INC. (US) | 2022-04-21 | — | — | US | disclosed |
| US-11214565-B2 | Compound, compositions, and methods | DENALI THERAPEUTICS INC. (US) | 2022-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220119371-A1 | COMPOUND, COMPOSITIONS, AND METHODS | LRRK2, PARK7, SNCA | LRRK2 1/4885CYP1A2 3146/4885TTK 929/4885 |
| US-11214565-B2 | Compound, compositions, and methods | LRRK2, PARK7, MAPT | LRRK2 1/4885CYP1A2 3151/4885TTK 900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.