Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25013559 | 0.90 | RIPK1 (0.33) | RIPK1 | |
| SCHEMBL25012658 | 0.89 | TMPRSS2 (0.31) | TMPRSS2RIPK1 | |
| SCHEMBL23696910 | 0.89 | TMPRSS2 (0.40) | TMPRSS2RIPK1 | |
| SCHEMBL24149112 | 0.86 | RIPK1 (0.31) | RIPK1 | |
| SCHEMBL30269859 | 0.86 | TMPRSS2 (0.39) | TMPRSS2RIPK1 | |
| SCHEMBL25012669 | 0.86 | TMPRSS2 (0.39) | TMPRSS2RIPK1 | |
| SCHEMBL26206282 | 0.82 | TMPRSS2 (0.45) | TMPRSS2RIPK1 | |
| SCHEMBL24148770 | 0.81 | TMPRSS2 (0.39) | TMPRSS2 | |
| SCHEMBL31684216 | 0.80 | TMPRSS2 (0.38) | TMPRSS2RIPK1 | |
| SCHEMBL31684068 | 0.80 | TMPRSS2 (0.38) | TMPRSS2RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021262826-A2 | 1'-CYANO NUCLEOSIDE ANALOGS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2021-12-30 | — | — | WO | disclosed |