Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24149833 | 0.91 | DOT1L (0.36) | DOT1L | |
| SCHEMBL24149666 | 0.90 | DOT1L (0.39) | DOT1LGRM2 | |
| SCHEMBL24149617 | 0.88 | DOT1L (0.36) | DOT1L | |
| SCHEMBL24149850 | 0.88 | DOT1L (0.36) | DOT1L | |
| SCHEMBL24148995 | 0.84 | — | — | |
| SCHEMBL24158150 | 0.83 | DOT1L (0.33) | DOT1L | |
| SCHEMBL24149846 | 0.82 | DOT1L (0.37) | DOT1L | |
| SCHEMBL24058189 | 0.82 | DOT1L (0.33) | DOT1L | |
| SCHEMBL24057868 | 0.81 | DOT1L (0.34) | DOT1L | |
| SCHEMBL24149020 | 0.79 | DOT1L (0.37) | DOT1LGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021262826-A2 | 1'-CYANO NUCLEOSIDE ANALOGS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2021-12-30 | — | — | WO | disclosed |