SCHEMBL24058189

SCHEMBL24058189

CCCC(CC)COC(=O)CN[P@](OC[C@@H]1CCC(c2ccc3c(N)ncnn23)O1)Oc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ DOT1L Q8TEK3 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24158150 0.96 DOT1L (0.33) DOT1L
SCHEMBL24148995 0.90 — —
SCHEMBL20144187 0.86 DOT1L (0.34) DOT1L
SCHEMBL24057868 0.86 DOT1L (0.34) DOT1L
SCHEMBL19504136 0.85 DOT1L (0.33) DOT1L
SCHEMBL24058292 0.85 DOT1L (0.33) DOT1L
SCHEMBL24148935 0.82 DOT1L (0.38) DOT1L
SCHEMBL24058411 0.80 DOT1L (0.32) DOT1L
SCHEMBL22355507 0.80 DOT1L (0.32) DOT1L
SCHEMBL19504133 0.80 DOT1L (0.32) DOT1L

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3212175-B1 METHODS FOR THE PREPARATION OF RIBOSIDES GILEAD SCIENCES INC (US) 2021-11-24 — — EP disclosed
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