Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25012918 | 0.92 | DOT1L (0.30) | DOT1L | |
| SCHEMBL24149370 | 0.92 | DOT1L (0.31) | DOT1L | |
| SCHEMBL25012695 | 0.91 | — | — | |
| SCHEMBL25013598 | 0.91 | — | — | |
| SCHEMBL25012545 | 0.87 | BTN3A1 (0.33) | — | |
| SCHEMBL24148708 | 0.87 | CYP3A4 (0.32) | — | |
| SCHEMBL18636608 | 0.87 | CYP3A4 (0.32) | — | |
| SCHEMBL25012565 | 0.86 | BTN3A1 (0.34) | — | |
| SCHEMBL30939785 | 0.86 | — | — | |
| SCHEMBL24148647 | 0.85 | TMPRSS2 (0.42) | DOT1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021262826-A2 | 1'-CYANO NUCLEOSIDE ANALOGS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2021-12-30 | — | — | WO | disclosed |