Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTN3A1 | O00481 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25012565 | 0.93 | BTN3A1 (0.34) | BTN3A1CYP3A4CYP2C9RIPK1 | |
| SCHEMBL24148708 | 0.89 | CYP3A4 (0.32) | BTN3A1CYP3A4CYP2C9RIPK1 | |
| SCHEMBL18636608 | 0.89 | CYP3A4 (0.32) | BTN3A1CYP3A4CYP2C9RIPK1 | |
| SCHEMBL24149678 | 0.87 | DOT1L (0.31) | — | |
| SCHEMBL24148988 | 0.86 | TMPRSS2 (0.39) | BTN3A1CYP3A4CYP2C9RIPK1 | |
| SCHEMBL25012893 | 0.86 | BTN3A1 (0.32) | BTN3A1 | |
| SCHEMBL25013589 | 0.85 | BTN3A1 (0.31) | BTN3A1 | |
| SCHEMBL24149496 | 0.83 | CYP3A4 (0.37) | BTN3A1CYP3A4CYP2C9RIPK1 | |
| SCHEMBL25012912 | 0.83 | CSNK1A1 (0.31) | — | |
| SCHEMBL25012629 | 0.83 | CYP3A4 (0.33) | BTN3A1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230040586-A1 | 1'-CYANO NUCLEOSIDE ANALOGS AND USES THEREOF | GILEAD SCIENCES, INC. | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230040586-A1 | 1'-CYANO NUCLEOSIDE ANALOGS AND USES THEREOF | TYMP, PNP, DUT | BTN3A1 3427/4885CYP3A4 1932/4885CYP2C9 2637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.