Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SCN1B | Q07699 | 4/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | SNCA | P37840 | 1/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 2/20 | 0.31 |
| ▸ | CASP7 | P55210 | 2/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24151584 | 0.90 | TRPA1 (0.42) | TRPA1MAPTPOLBSTAT3SMN1; SMN2 | |
| SCHEMBL24152462 | 0.88 | TRPA1 (0.41) | TRPA1MAPTPOLBSTAT3SMN1; SMN2 | |
| SCHEMBL24151587 | 0.88 | TRPA1 (0.42) | TRPA1MAPTPOLBSTAT3SMN1; SMN2 | |
| SCHEMBL24152367 | 0.88 | TRPA1 (0.41) | TRPA1MAPTPOLBSTAT3SMN1; SMN2 | |
| SCHEMBL24152464 | 0.86 | TRPA1 (0.41) | TRPA1MAPTPOLBSTAT3SMN1; SMN2 | |
| SCHEMBL24152847 | 0.86 | TRPA1 (0.41) | TRPA1MAPTPOLBSTAT3SMN1; SMN2 | |
| SCHEMBL24153255 | 0.85 | TRPA1 (0.40) | TRPA1MAPTPOLBSTAT3SMN1; SMN2 | |
| SCHEMBL24152461 | 0.85 | TRPA1 (0.40) | TRPA1MAPTPOLBSTAT3SMN1; SMN2 | |
| SCHEMBL24152465 | 0.84 | TRPA1 (0.40) | TRPA1MAPTPOLBSTAT3SMN1; SMN2 | |
| SCHEMBL24153269 | 0.84 | TRPA1 (0.40) | TRPA1MAPTPOLBSTAT3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |