Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | APP | P05067 | 4/20 | 0.46 |
| ▸ | SNCA | P37840 | 4/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | MDM4 | O15151 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24152898 | 0.94 | MAPT (0.46) | MAPTAPPSNCAERBB2CA1 | |
| SCHEMBL24152866 | 0.92 | MAPT (0.46) | MAPTAPPSNCAERBB2CA1 | |
| SCHEMBL24152903 | 0.86 | PDE4A (0.45) | MAPTAPPSNCAPDE4APDE4B | |
| SCHEMBL24152884 | 0.86 | ERBB2 (0.43) | MAPTAPPSNCAERBB2PDE4A | |
| SCHEMBL24152509 | 0.85 | GSK3B (0.39) | MAPTAPPSNCAERBB2PDE4A | |
| SCHEMBL24152887 | 0.85 | MAPT (0.39) | MAPTAPPSNCAERBB2PDE4A | |
| SCHEMBL24152374 | 0.83 | ALDH1A1 (0.42) | MAPTAPPSNCAERBB2MEN1 | |
| SCHEMBL24152384 | 0.83 | MAPT (0.42) | MAPTAPPSNCAMEN1KMT2A | |
| SCHEMBL24152383 | 0.83 | PARP1 (0.37) | MAPTAPPSNCAERBB2MEN1 | |
| SCHEMBL24152370 | 0.81 | MAPT (0.34) | MAPTAPPSNCAERBB2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |