Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY1 | Q08828 | 6/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.68 |
| ▸ | MEN1 | O00255 | 5/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | LMNA | P02545 | 7/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.60 |
| ▸ | USP2 | O75604 | 3/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.59 |
| ▸ | HTT | P42858 | 5/20 | 0.59 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 4/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20598023 | 0.84 | ADCY1 (1.00) | ADCY1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL20598091 | 0.83 | ADCY1 (1.00) | ADCY1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL24145665 | 0.83 | ADCY1 (0.61) | ADCY1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL22589730 | 0.82 | ADCY1 (0.74) | ADCY1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL22589787 | 0.82 | ADCY1 (0.82) | ADCY1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL20597939 | 0.81 | ADCY1 (1.00) | ADCY1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL20598288 | 0.81 | ADCY1 (1.00) | ADCY1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL22589707 | 0.78 | ADCY1 (0.74) | ADCY1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL22589718 | 0.78 | ADCY1 (0.78) | ADCY1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL27170272 | 0.77 | KDM4E (0.57) | ADCY1KDM4EMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021258272-A1 | COMPOUNDS AND THEIR USES AS MIF INHIBITORS | Nanjing Immunophage Biotech Co., Ltd. (CN) | 2021-12-30 | — | — | WO | disclosed |