SCHEMBL24154573

SCHEMBL24154573

c1ccc(N(c2ccccc2)c2ccc(-c3ccc4ccccc4c3N(c3ccccc3)c3ccccc3)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.38
CYP1A2 P05177 3/20 0.38
TDP1 Q9NUW8 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
KDM4E B2RXH2 2/20 0.38
MAPT P10636 2/20 0.38
CYP3A4 P08684 2/20 0.38
CYP2D6 P10635 2/20 0.38
CYP2C9 P11712 2/20 0.38
CYP2C19 P33261 2/20 0.38
HSD17B10 Q99714 2/20 0.37
CYP2A6 P11509 1/20 0.37
TSHR P16473 1/20 0.37
HPRT1 P00492 1/20 0.34
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
CRHBP P24387 1/20 0.33
ATM Q13315 1/20 0.33
CRHR2 Q13324 1/20 0.33
TLR9 Q9NR96 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24154109 0.97 ALDH1A1 (0.36) ALDH1A1CYP1A2TDP1L3MBTL1KDM4E
SCHEMBL23430357 0.97 ALDH1A1 (0.36) ALDH1A1CYP1A2TDP1L3MBTL1KDM4E
SCHEMBL24154418 0.97 ALDH1A1 (0.36) ALDH1A1CYP1A2TDP1L3MBTL1KDM4E
SCHEMBL28402730 0.93 ALDH1A1 (0.39) ALDH1A1CYP1A2TDP1L3MBTL1KDM4E
SCHEMBL24154171 0.92 GSTP1 (0.34) ALDH1A1CYP1A2TDP1L3MBTL1KDM4E
SCHEMBL24154112 0.91 ESR1 (0.40) ALDH1A1CYP1A2TDP1L3MBTL1KDM4E
SCHEMBL24153674 0.89 ESR1 (0.37) ALDH1A1KDM4EMAPTMEN1KMT2A
SCHEMBL29222173 0.88 ALDH1A1 (0.35) ALDH1A1CYP1A2TDP1L3MBTL1KDM4E
SCHEMBL26420428 0.86 TDP1 (0.38) ALDH1A1CYP1A2TDP1L3MBTL1KDM4E
SCHEMBL24029668 0.85 HPRT1 (0.36) ALDH1A1CYP1A2TDP1L3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021261962-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2021-12-30 WO disclosed