Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY1 | Q08828 | 6/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.61 |
| ▸ | LMNA | P02545 | 6/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30343012 | 0.92 | ADCY1 (0.60) | ADCY1KDM4ELMNANPC1RAB9A | |
| SCHEMBL24146035 | 0.92 | ADCY1 (0.60) | ADCY1KDM4ELMNANPC1RAB9A | |
| SCHEMBL30343003 | 0.91 | KDM4E (0.72) | ADCY1KDM4ELMNANPC1RAB9A | |
| SCHEMBL24145812 | 0.91 | KDM4E (0.72) | ADCY1KDM4ELMNANPC1RAB9A | |
| SCHEMBL29032402 | 0.89 | ADCY1 (0.63) | ADCY1KDM4ELMNANPC1RAB9A | |
| SCHEMBL30343011 | 0.88 | ADCY1 (0.55) | ADCY1KDM4ELMNANPC1RAB9A | |
| SCHEMBL27170276 | 0.88 | ADCY1 (0.55) | ADCY1KDM4ELMNANPC1RAB9A | |
| SCHEMBL24146061 | 0.85 | KDM4E (0.63) | ADCY1KDM4ELMNANPC1RAB9A | |
| SCHEMBL24145665 | 0.85 | ADCY1 (0.61) | ADCY1KDM4ELMNANPC1RAB9A | |
| SCHEMBL24145828 | 0.85 | ADCY1 (0.61) | ADCY1KDM4ELMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021258272-A1 | COMPOUNDS AND THEIR USES AS MIF INHIBITORS | Nanjing Immunophage Biotech Co., Ltd. (CN) | 2021-12-30 | — | — | WO | disclosed |