SCHEMBL24155355

SCHEMBL24155355

c1ccc(-c2ccc(N(c3nc4ccccc4s3)c3nc(-c4ccccc4)nc4ccccc34)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.52
CYP2D6 P10635 5/20 0.52
SMN1; SMN2 Q16637 4/20 0.52
ALDH1A1 P00352 4/20 0.52
CYP1A2 P05177 4/20 0.52
CYP2C9 P11712 4/20 0.52
GLA P06280 3/20 0.52
KDM4E B2RXH2 3/20 0.52
HPGD P15428 3/20 0.52
CYP2C19 P33261 3/20 0.52
TSHR P16473 2/20 0.52
HIF1A Q16665 2/20 0.52
LMNA P02545 2/20 0.52
MAPT P10636 2/20 0.52
RECQL P46063 1/20 0.52
PDE5A O76074 3/20 0.49
ACP1 P24666 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.48
TP53 P04637 4/20 0.45
GBA1 P04062 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21709267 0.84 CYP3A4 (0.67) CYP3A4CYP2D6SMN1; SMN2ALDH1A1CYP1A2
SCHEMBL24155353 0.84 APP (0.50) CYP3A4CYP2D6SMN1; SMN2ALDH1A1CYP1A2
SCHEMBL24155351 0.82 APP (0.49) CYP3A4CYP2D6SMN1; SMN2ALDH1A1CYP1A2
SCHEMBL24155435 0.81 APP (0.48) CYP3A4CYP2D6SMN1; SMN2ALDH1A1CYP1A2
SCHEMBL24155352 0.78 APP (0.40) CYP3A4CYP2D6SMN1; SMN2ALDH1A1CYP1A2
SCHEMBL16484012 0.74 NPC1 (0.51) CYP3A4CYP2D6SMN1; SMN2ALDH1A1CYP1A2
SCHEMBL24155354 0.74 RAB9A (0.49) CYP3A4CYP2D6SMN1; SMN2ALDH1A1CYP1A2
SCHEMBL14516046 0.74 APP (0.39) CYP3A4SMN1; SMN2ALDH1A1GLAKDM4E
SCHEMBL27257470 0.73 APP (0.43) SMN1; SMN2ALDH1A1GLAKDM4EHPGD
SCHEMBL24155438 0.73 RAB9A (0.44) CYP3A4CYP2D6SMN1; SMN2ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021261851-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME ORGANIC ELECTRIC ELEMENT 덕산네오룩스 주식회사 2021-12-30 WO disclosed