SCHEMBL24155437

SCHEMBL24155437

c1ccc2sc(N(c3ccc(-c4cncnc4)cc3)c3ccc(-c4cncnc4)cc3)nc2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.44
NPC1 O15118 6/20 0.42
RAB9A P51151 6/20 0.42
PDE10A Q9Y233 1/20 0.41
ATM Q13315 1/20 0.41
CYP3A4 P08684 4/20 0.40
ALDH1A1 P00352 3/20 0.39
ALOX15 P16050 2/20 0.39
ADRA2A P08913 1/20 0.39
FBP1 P09467 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
DRD2 P14416 1/20 0.39
HPGD P15428 1/20 0.39
ADRA2B P18089 1/20 0.39
ADRA2C P18825 1/20 0.39
DRD1 P21728 1/20 0.39
MC5R P33032 1/20 0.39
OPRM1 P35372 1/20 0.39
DRD3 P35462 1/20 0.39
OPRK1 P41145 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24155353 0.86 APP (0.50) APPNPC1RAB9ACYP3A4ALDH1A1
SCHEMBL24155351 0.85 APP (0.49) APPNPC1RAB9ACYP3A4ALDH1A1
SCHEMBL24155435 0.84 APP (0.48) APPNPC1RAB9ACYP3A4ALDH1A1
SCHEMBL16484012 0.80 NPC1 (0.51) APPNPC1RAB9ACYP3A4ALDH1A1
SCHEMBL24155354 0.77 RAB9A (0.49) APPNPC1RAB9APDE10ACYP3A4
SCHEMBL27257470 0.75 APP (0.43) APPNPC1RAB9APDE10AALDH1A1
SCHEMBL24155438 0.75 RAB9A (0.44) APPNPC1RAB9ACYP3A4ALDH1A1
SCHEMBL14516046 0.74 APP (0.39) APPNPC1RAB9ACYP3A4ALDH1A1
SCHEMBL22007069 0.74 PIK3CA (0.56) APPALDH1A1HPGDLMNASMN1; SMN2
SCHEMBL14515940 0.72 SMN1; SMN2 (0.43) APPNPC1RAB9ACYP3A4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021261851-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME ORGANIC ELECTRIC ELEMENT 덕산네오룩스 주식회사 2021-12-30 WO disclosed