Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 3/20 | 0.61 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 5/20 | 0.47 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 5/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24155661 | 0.82 | NPC1 (0.60) | PIK3CAPIK3CDMEN1KMT2ANPC1 | |
| SCHEMBL20687402 | 0.80 | PIK3CD (0.73) | PIK3CAPIK3CDNPC1RAB9AEGFR | |
| SCHEMBL24155896 | 0.80 | MEN1 (0.55) | MEN1KMT2ANPC1GAARAB9A | |
| SCHEMBL24155533 | 0.79 | MEN1 (0.54) | PIK3CAPIK3CDMEN1KMT2ANPC1 | |
| SCHEMBL8644295 | 0.78 | PIK3CA (0.73) | PIK3CAPIK3CDNPC1RAB9AEGFR | |
| SCHEMBL24156361 | 0.77 | MEN1 (0.58) | PIK3CDMEN1KMT2ANPC1GAA | |
| Diphenylether SCHEMBL28398421 | 0.74 | EGFR (0.74) | PIK3CAPIK3CDKMT2AEGFRHTT | |
| SCHEMBL24156338 | 0.73 | NPC1 (0.54) | MEN1KMT2ANPC1GAARAB9A | |
| SCHEMBL17231469 | 0.73 | PIK3CA (0.67) | PIK3CAPIK3CDNPC1RAB9AEGFR | |
| SCHEMBL24155468 | 0.72 | NPC1 (0.58) | PIK3CDMEN1KMT2ANPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210403456-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF EPILEPSY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2021-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210403456-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF EPILEPSY | SLC6A11, SCN1A, SCN1B | PIK3CA 3791/4885PIK3CD 3693/4885MEN1 450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.