Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.39 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PAK4 | O96013 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.36 |
| ▸ | CHUK | O15111 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | BCL6 | P41182 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2415211 | 0.88 | GAA (0.43) | OGFRL1GAASCN9A | |
| SCHEMBL2421089 | 0.88 | KMT2A (0.38) | PDE10AOGFRL1CCNE2CDK4CCND1 | |
| SCHEMBL2411637 | 0.87 | CCNE2 (0.42) | PDE10AOGFRL1CCNE2CDK4CCND1 | |
| SCHEMBL2414751 | 0.87 | PDE10A (0.45) | PDE10ACCNE2CDK4CCND1CCNE1 | |
| SCHEMBL2417287 | 0.85 | KMT2A (0.42) | PDE10AOGFRL1CCNE2CDK4CCND1 | |
| SCHEMBL2415998 | 0.82 | CCNE2 (0.40) | PDE10ACCNE2CDK4CCND1CCNE1 | |
| SCHEMBL2412675 | 0.82 | CHUK (0.47) | PDE10ACCNE2CDK4CCND1CCNE1 | |
| SCHEMBL2415857 | 0.82 | PDE10A (0.38) | PDE10ACCNE2CDK4CCND1CCNE1 | |
| SCHEMBL2413721 | 0.82 | GAA (0.42) | OGFRL1GAASCN9A | |
| SCHEMBL2410500 | 0.81 | GAA (0.38) | OGFRL1GAASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1312606-B1 | 2,5-diaminopyridine oxidation bases and their use for dyeing of keratin fibres | OREAL (FR) | 2011-09-21 | — | — | EP | claimed |
| CN-1250192-C | 2,5-diaminopyridine oxidation color display alkali for dyeing keratin fibre | OREAL (FR) | 2006-04-12 | — | — | CN | claimed |
| US-6837908-B2 | 2,5-diaminopyridine oxidation bases for the dyeing of keratin fibres | L'OREAL S.A. (FR) | 2005-01-04 | — | — | US | claimed |
| US-20030163876-A1 | Novel 2,5-diaminopyridine oxidation bases for the dyeing of keratin fibres | L'OREAL S.A. (FR) | 2003-09-04 | — | — | US | claimed |
| CN-1425365-A | 2,5-diaminopyridine oxidation color display alkali for dyeing keratin fibre | OREAL (FR) | 2003-06-25 | — | — | CN | claimed |
| EP-1312606-A1 | 2,5-diaminopyridine oxidation bases and their use for dyeing of keratin fibres | L'OREAL (FR) | 2003-05-21 | — | — | EP | claimed |
| EP-1312606-B1 | 2,5-diaminopyridine oxidation bases and their use for dyeing of keratin fibres | OREAL (FR) | 2011-09-21 | — | — | EP | disclosed |
| CN-1250192-C | 2,5-diaminopyridine oxidation color display alkali for dyeing keratin fibre | OREAL (FR) | 2006-04-12 | — | — | CN | disclosed |
| US-6837908-B2 | 2,5-diaminopyridine oxidation bases for the dyeing of keratin fibres | L'OREAL S.A. (FR) | 2005-01-04 | — | — | US | disclosed |
| US-20030163876-A1 | Novel 2,5-diaminopyridine oxidation bases for the dyeing of keratin fibres | L'OREAL S.A. (FR) | 2003-09-04 | — | — | US | disclosed |
| CN-1425365-A | 2,5-diaminopyridine oxidation color display alkali for dyeing keratin fibre | OREAL (FR) | 2003-06-25 | — | — | CN | disclosed |
| EP-1312606-A1 | 2,5-diaminopyridine oxidation bases and their use for dyeing of keratin fibres | L'OREAL (FR) | 2003-05-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030163876-A1 | Novel 2,5-diaminopyridine oxidation bases for the dyeing of keratin fibres | KRT18, DPYD, DSP | PDE10A 3263/4885OGFRL1 2645/4885CCNE2 3961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.