SCHEMBL241567

SCHEMBL241567

CC(C)(C)OC(=O)N1[C@H](C(N)=O)C[C@@H]2CCC[C@@H]21

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.44
CHRM1 P11229 1/20 0.44
CHRM3 P20309 1/20 0.44
PREP P48147 4/20 0.41
GPR119 Q8TDV5 5/20 0.36
HSD11B1 P28845 1/20 0.36
NR1H2 P55055 1/20 0.35
HPGD P15428 1/20 0.35
DPP4 P27487 1/20 0.34
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12684291 1.00 CHRM2 (0.44) CHRM2CHRM1CHRM3PREPGPR119
SCHEMBL241566 1.00 CHRM2 (0.44) CHRM2CHRM1CHRM3PREPGPR119
SCHEMBL6367295 0.97 CHRM2 (0.44) CHRM2CHRM1CHRM3PREPGPR119
SCHEMBL241194 0.87 CHRM2 (0.45) CHRM2CHRM1CHRM3PREPGPR119
SCHEMBL18300694 0.87 CHRM2 (0.45) CHRM2CHRM1CHRM3PREPGPR119
SCHEMBL12684327 0.87 CHRM2 (0.45) CHRM2CHRM1CHRM3PREPGPR119
SCHEMBL18300764 0.87 CHRM2 (0.45) CHRM2CHRM1CHRM3PREPGPR119
SCHEMBL1759496 0.87 CHRM2 (0.45) CHRM2CHRM1CHRM3PREPGPR119
SCHEMBL18829369 0.87 CHRM2 (0.45) CHRM2CHRM1CHRM3PREPGPR119
SCHEMBL14733315 0.87 CHRM2 (0.45) CHRM2CHRM1CHRM3PREPGPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230285378-A1 Anti-Viral Compounds ABBVIE INC. (US) 2023-09-14 US disclosed
US-20230285378-A1 Anti-Viral Compounds ABBVIE INC. (US) 2023-09-14 US disclosed
US-20230285378-A1 Anti-Viral Compounds ABBVIE INC. (US) 2023-09-14 US disclosed
EP-3438106-A1 ANTI-VIRAL COMPOUNDS AbbVie Ireland Unlimited Company (IE) 2019-02-06 EP disclosed
US-20190015402-A1 Anti-Viral Compounds ABBVIE INC. (US) 2019-01-17 US disclosed
US-20190015402-A1 Anti-Viral Compounds ABBVIE INC. (US) 2019-01-17 US disclosed
US-10039754-B2 Anti-viral compounds ABBVIE INC. (US) 2018-08-07 US disclosed
US-10039754-B2 Anti-viral compounds ABBVIE INC. (US) 2018-08-07 US disclosed
US-10039754-B2 Anti-viral compounds ABBVIE INC. (US) 2018-08-07 US disclosed
US-10028937-B2 Anti-viral compounds ABBVIE INC. (US) 2018-07-24 US disclosed
US-20120220562-A1 Anti-Viral Compounds Abbott Labaoratories (US) 2012-08-30 US disclosed
US-20120220562-A1 Anti-Viral Compounds Abbott Labaoratories (US) 2012-08-30 US disclosed
US-20120004196-A1 Anti-Viral Compounds Abbott Labaoratories (US) 2012-01-05 US disclosed
US-20120004196-A1 Anti-Viral Compounds Abbott Labaoratories (US) 2012-01-05 US disclosed
US-20110207699-A1 Anti-Viral Compounds Abbott Labaoratories (US) 2011-08-25 US disclosed
US-20110207699-A1 Anti-Viral Compounds Abbott Labaoratories (US) 2011-08-25 US disclosed
US-20110207699-A1 Anti-Viral Compounds Abbott Labaoratories (US) 2011-08-25 US disclosed
US-20110092415-A1 Anti-Viral Compounds Abbott Labaoratories (US) 2011-04-21 US disclosed
US-20110092415-A1 Anti-Viral Compounds Abbott Labaoratories (US) 2011-04-21 US disclosed
US-20110092415-A1 Anti-Viral Compounds Abbott Labaoratories (US) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10028937-B2 Anti-viral compounds HAVCR2, EIF2AK2, MAVS CHRM2 4875/4885CHRM1 4854/4885CHRM3 4792/4885
US-20230285378-A1 Anti-Viral Compounds HAVCR2, EIF2AK2, MAVS CHRM2 4875/4885CHRM1 4854/4885CHRM3 4792/4885
US-20120220562-A1 Anti-Viral Compounds HAVCR2, EIF2AK2, MAVS CHRM2 4875/4885CHRM1 4854/4885CHRM3 4792/4885
US-20110092415-A1 Anti-Viral Compounds HAVCR2, EIF2AK2, MAVS CHRM2 4875/4885CHRM1 4854/4885CHRM3 4792/4885
US-20110207699-A1 Anti-Viral Compounds HAVCR2, EIF2AK2, MAVS CHRM2 4875/4885CHRM1 4854/4885CHRM3 4792/4885
US-20190015402-A1 Anti-Viral Compounds HAVCR2, EIF2AK2, MAVS CHRM2 4875/4885CHRM1 4854/4885CHRM3 4792/4885
US-20120004196-A1 Anti-Viral Compounds HAVCR2, EIF2AK2, MAVS CHRM2 4875/4885CHRM1 4854/4885CHRM3 4792/4885
US-10039754-B2 Anti-viral compounds HAVCR2, EIF2AK2, MAVS CHRM2 4875/4885CHRM1 4854/4885CHRM3 4792/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.