SCHEMBL2415700

SCHEMBL2415700

CC(=O)OC(=O)c1cccc(C)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.55
LMNA P02545 1/20 0.52
HDAC8 Q9BY41 1/20 0.52
HDAC6 Q9UBN7 1/20 0.52
KMT2A Q03164 4/20 0.50
ESR1 P03372 2/20 0.50
MEN1 O00255 2/20 0.50
POLB P06746 1/20 0.50
ESR2 Q92731 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.49
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
MAPT P10636 2/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
GAA P10253 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
KDM4E B2RXH2 1/20 0.48
MAPK1 P28482 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4188727 0.90 PARP1 (0.61) PARP1HDAC8HDAC6KMT2AESR1
SCHEMBL31316346 0.90 PARP1 (0.61) PARP1HDAC8HDAC6KMT2AESR1
SCHEMBL123941 0.88 TDP1 (0.44) LMNAKMT2AESR1MEN1POLB
SCHEMBL6113333 0.85 SMN1; SMN2 (0.58) PARP1LMNAHDAC8HDAC6KMT2A
Hydrochloric Acid SCHEMBL27347414 0.83 SMN1; SMN2 (0.56) PARP1HDAC8HDAC6KMT2AESR1
SCHEMBL28348794 0.83 PARP1 (0.63) PARP1HDAC8HDAC6KMT2AESR1
Ethylene Glycol SCHEMBL28453593 0.83 PARP1 (0.53) PARP1HDAC8HDAC6KMT2AESR1
SCHEMBL11488211 0.83 PARP1 (0.53) PARP1HDAC8HDAC6KMT2AESR1
SCHEMBL44313 0.82 PARP1 (0.61) PARP1LMNAHDAC8HDAC6KMT2A
SCHEMBL29397067 0.82 PARP1 (0.61) PARP1LMNAHDAC8HDAC6KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3871857-B1 POLYMER MEMBER PRODUCTION METHOD ASICS CORP (JP) 2024-02-07 EP disclosed
US-11884003-B2 Method for producing polymer member ASICS CORPORATION (JP) 2024-01-30 US disclosed
CN-110573503-B Pyrrole derivatives as PLK1 inhibitors 圣提内尔肿瘤学有限公司 2023-03-17 CN disclosed
CN-110552018-B Method for synthesizing 1-naphthol compound based on electrochemical intermolecular cyclization 广西师范大学 2021-03-05 CN disclosed
CN-110552018-A Method for synthesizing 1-naphthol compound based on electrochemical intermolecular cyclization UNIV GUANGXI NORMAL 2019-12-10 CN disclosed
WO-2017123568-A2 METHODS FOR THE TREATMENT OF MYELOID DERIVED SUPPRESSOR CELLS RELATED DISORDERS THE ROCKEFELLER UNIVERSITY (US) 2017-07-20 WO disclosed
EP-2951177-A1 IMIDAZOPYRIDINE COMPOUNDS AND USES THEREOF Neomed Institute (CA) 2015-12-09 EP disclosed
CN-102675092-B Method for preparing 2-aryl-2,2-dimethyl methyl acetate JIANGSU ZHONGDAN PHARMACEUTICAL RES CO LTD 2014-11-05 CN disclosed
WO-2014117274-A1 IMIDAZOPYRIDINE COMPOUNDS AND USES THEREOF NEOMED INSTITUTE (CA) 2014-08-07 WO disclosed
US-8288462-B2 Polyolefin resin composition ADEKA CORPORATION (JP) 2012-10-16 US disclosed
CN-101296949-B Method for preparing polymer particles VALSPAR SOURCING INC 2012-05-30 CN disclosed
US-20110218279-A1 POLYOLEFIN RESIN COMPOSITION ADEKA CORPORATION (JP) 2011-09-08 US disclosed
CN-101296949-A Method for preparing polymer particles VALSPAR SOURCING INC (US) 2008-10-29 CN disclosed
EP-1215216-B1 Cellulose ester of aromatic carboxylic acid FUJI PHOTO FILM CO LTD (JP) 2005-07-27 EP disclosed
EP-1215216-A1 Cellulose ester of aromatic carboxylic acid FUJI PHOTO FILM CO., LTD. (JP) 2002-06-19 EP disclosed