SCHEMBL4188727

SCHEMBL4188727

Cc1cccc(C(=O)OC(=O)c2cccc(C)c2)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.61
HDAC8 Q9BY41 1/20 0.57
HDAC6 Q9UBN7 1/20 0.57
KMT2A Q03164 4/20 0.54
MEN1 O00255 2/20 0.54
ESR1 P03372 2/20 0.54
POLB P06746 2/20 0.54
ESR2 Q92731 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.53
KCNK3 O14649 1/20 0.52
KCNH2 Q12809 1/20 0.52
KCNK9 Q9NPC2 1/20 0.52
HPGD P15428 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
NPC1 O15118 3/20 0.51
RAB9A P51151 3/20 0.51
MAPT P10636 2/20 0.51
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
GAA P10253 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31316346 1.00 PARP1 (0.61) PARP1HDAC8HDAC6KMT2AMEN1
SCHEMBL6113333 0.94 SMN1; SMN2 (0.58) PARP1HDAC8HDAC6KMT2AMEN1
SCHEMBL11488211 0.92 PARP1 (0.53) PARP1HDAC8HDAC6KMT2AMEN1
Hydrochloric Acid SCHEMBL27347414 0.92 SMN1; SMN2 (0.56) PARP1HDAC8HDAC6KMT2AMEN1
Ethylene Glycol SCHEMBL28453593 0.92 PARP1 (0.53) PARP1HDAC8HDAC6KMT2AMEN1
SCHEMBL22290044 0.91 POLB (0.56) PARP1HDAC8HDAC6KMT2AMEN1
SCHEMBL2415700 0.90 PARP1 (0.55) PARP1HDAC8HDAC6KMT2AMEN1
SCHEMBL28348794 0.88 PARP1 (0.63) PARP1HDAC8HDAC6KMT2AMEN1
SCHEMBL44313 0.87 PARP1 (0.61) PARP1HDAC8HDAC6KMT2AMEN1
SCHEMBL29397067 0.87 PARP1 (0.61) PARP1HDAC8HDAC6KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116584486-B Antibacterial agent and preparation method and application thereof 江西清晨纸业有限公司 2025-04-25 CN claimed
CN-116584486-A Antibacterial agent and preparation method and application thereof 江西清晨纸业有限公司 2023-08-15 CN claimed
CN-111234070-B Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2022-03-01 CN claimed
CN-111234073-B Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2021-12-31 CN claimed
CN-111234073-A Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2020-06-05 CN claimed
CN-111234070-A Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2020-06-05 CN claimed
US-20180273819-A1 THERMAL ENERGY STORAGE PHASE AND TEMPERATURE STABILIZATION CHANGE MATERIALS COMPRISING TRIAMINES AND METHODS FOR MAKING AND USING THEM ENTROPY SOLUTIONS LLC (US) 2018-09-27 US claimed
WO-2016179028-A1 THERMAL ENERGY STORAGE PHASE AND TEMPERATURE STABILIZATION CHANGE MATERIALS AND METHODS FOR MAKING AND USING THEM ENTROPY SOLUTIONS, LLC. (US) 2016-11-10 WO claimed
US-5731423-A OXIDATION TRANSCELL TECHNOLOGIES, INC. (US) 1998-03-24 US claimed
WO-1997034867-A1 PROCESS FOR PREPARING SULFOXIDES TRANSCELL TECHNOLOGIES, INC. (US) 1997-09-25 WO claimed
US-5097066-A Dissolving 4,4'-dicarboxydiphenyl ether, 4,4'-carboxybis/ benzoic acid/ or terephthalic acid in monocarboxylic acid anhydride, removing impurities from solution, recovering purified acid by recrystallization or hydrolysis AMOCO CORPORATION (US) 1992-03-17 US claimed
JP-8067895-A None JP disclosed
CN-116584486-B Antibacterial agent and preparation method and application thereof 江西清晨纸业有限公司 2025-04-25 CN disclosed
WO-2025015175-A2 HEATING, VENTILATION, AND AIR CONDITIONING (HVAC) SYSTEMS AND METHODS FOR USING SAME STASIS ENERGY GROUP, LLC (US) 2025-01-16 WO disclosed
CN-116584486-A Antibacterial agent and preparation method and application thereof 江西清晨纸业有限公司 2023-08-15 CN disclosed
US-4018787-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1977-04-19 US disclosed
US-4009196-A HYPOTENSIVE AGENTS, BRONCHODILATORS, PROSTAGLANDIN ANALOGS TEIJIN LIMITED (JA) 1977-02-22 US disclosed
US-3970671-A XANTHENE, PRESSURE SENSITIVE KANZAKI PAPER MANUFACTURING CO., LTD. (JA) 1976-07-20 US disclosed
US-3947471-A CHROMOGENIC SUMITOMO CHEMICAL COMPANY, LTD. (JA) 1976-03-30 US disclosed
JP-H00867895-A 0001-01-01 JP disclosed