Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 6/20 | 0.46 |
| ▸ | ANPEP | P15144 | 5/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2991859 | 0.86 | LAP3 (0.50) | LAP3ANPEPACP3CYP1A2ALPI | |
| SCHEMBL2991862 | 0.86 | LAP3 (0.50) | LAP3ANPEPACP3CYP1A2ALPI | |
| SCHEMBL8697154 | 0.83 | LAP3 (0.47) | LAP3ANPEPACP3CYP1A2ALPI | |
| SCHEMBL9137977 | 0.81 | LAP3 (0.49) | LAP3ANPEPACP3CYP1A2ALPI | |
| SCHEMBL9137969 | 0.81 | LAP3 (0.49) | LAP3ANPEPACP3CYP1A2ALPI | |
| SCHEMBL21461885 | 0.80 | CYP1A2 (0.52) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL21461886 | 0.80 | CYP1A2 (0.52) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL3091871 | 0.77 | LAP3 (0.51) | LAP3ANPEPACP3CYP1A2ALPI | |
| SCHEMBL3091879 | 0.77 | LAP3 (0.51) | LAP3ANPEPACP3CYP1A2ALPI | |
| SCHEMBL31092852 | 0.77 | CYP1A2 (0.55) | CYP1A2ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106898-A1 | METHODS AND SYSTEMS FOR PREPARING IRREVERSIBLE INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2011-09-09 | — | — | WO | disclosed |