Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21626318 | 0.81 | GAA (0.36) | GAA | |
| SCHEMBL24458979 | 0.78 | GAA (0.37) | GAA | |
| SCHEMBL31637495 | 0.77 | ALDH1A1 (0.35) | GAA | |
| SCHEMBL23225441 | 0.77 | FOLH1 (0.38) | GAAMEN1KMT2A | |
| SCHEMBL21452653 | 0.75 | — | — | |
| SCHEMBL16118629 | 0.75 | KDM4E (0.37) | GAA | |
| SCHEMBL11224012 | 0.75 | KDM4E (0.37) | GAA | |
| SCHEMBL24458540 | 0.73 | IDO1 (0.30) | — | |
| SCHEMBL21452570 | 0.73 | ALDH1A1 (0.30) | — | |
| SCHEMBL24159127 | 0.72 | ALDH1A1 (0.33) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793565-B1 | MCL-1 INHIBITORS | GILEAD SCIENCES INC (US) | 2022-01-05 | — | — | EP | disclosed |