Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 20/20 | 0.57 |
| ▸ | NTRK3 | Q16288 | 8/20 | 0.57 |
| ▸ | NTRK2 | Q16620 | 6/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22454740 | 1.00 | NTRK1 (0.57) | NTRK1NTRK3NTRK2 | |
| SCHEMBL22454712 | 0.95 | NTRK1 (0.56) | NTRK1NTRK3NTRK2 | |
| SCHEMBL24503147 | 0.94 | NTRK1 (0.61) | NTRK1NTRK3NTRK2 | |
| SCHEMBL22454508 | 0.93 | NTRK1 (0.59) | NTRK1NTRK3NTRK2 | |
| SCHEMBL22454473 | 0.93 | NTRK1 (0.57) | NTRK1NTRK3NTRK2 | |
| SCHEMBL22454736 | 0.92 | NTRK1 (0.56) | NTRK1NTRK3NTRK2 | |
| SCHEMBL22454686 | 0.91 | NTRK1 (0.59) | NTRK1NTRK3NTRK2 | |
| SCHEMBL22454667 | 0.89 | NTRK1 (0.71) | NTRK1NTRK3NTRK2 | |
| SCHEMBL22454816 | 0.89 | NTRK1 (0.71) | NTRK1NTRK3NTRK2 | |
| SCHEMBL29684109 | 0.89 | NTRK1 (0.71) | NTRK1NTRK3NTRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3932923-B1 | PYRAZOLOPYRIMIDINE COMPOUND, PHARMACEUTICAL COMPOSITION, AND APPLICATION THEREFOR | UNIV CENTRAL CHINA NORMAL (CN) | 2023-05-03 | — | — | EP | disclosed |
| US-20220177477-A1 | PYRAZOLOPYRIMIDINE COMPOUND, PHARMACEUTICAL COMPOSITION, AND APPLICATION THEREFOR | Central China Normal University (CN) | 2022-06-09 | — | — | US | disclosed |
| EP-3932923-A1 | PYRAZOLOPYRIMIDINE COMPOUND, PHARMACEUTICAL COMPOSITION, AND APPLICATION THEREFOR | Central China Normal University (CN) | 2022-01-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220177477-A1 | PYRAZOLOPYRIMIDINE COMPOUND, PHARMACEUTICAL COMPOSITION, AND APPLICATION THEREFOR | ITK, TKFC, WEE2 | NTRK1 25/4885NTRK3 14/4885NTRK2 96/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.