Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 5/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18045974 | 0.77 | MAOB (0.46) | ALDH1A1GAALMNAMAPTMAOB | |
| SCHEMBL18047212 | 0.77 | NR1H4 (0.46) | ALDH1A1GAALMNAMAPTMAOB | |
| SCHEMBL18045975 | 0.77 | MAOB (0.46) | ALDH1A1GAALMNAMAPTMAOB | |
| SCHEMBL18047214 | 0.77 | NR1H4 (0.46) | ALDH1A1GAALMNAMAPTMAOB | |
| SCHEMBL18046319 | 0.77 | MAOB (0.47) | ALDH1A1GAALMNAMAPTMAOB | |
| SCHEMBL18046316 | 0.77 | MAOB (0.47) | ALDH1A1GAALMNAMAPTMAOB | |
| SCHEMBL18069273 | 0.74 | MAOB (0.42) | ALDH1A1GAALMNAMAPTMAOB | |
| SCHEMBL12677375 | 0.72 | MAOB (0.64) | ALDH1A1GAALMNAMAPTMAOB | |
| SCHEMBL12569877 | 0.71 | GAA (0.48) | ALDH1A1GAALMNAMAPTMAOB | |
| SCHEMBL9493078 | 0.70 | ALDH1A1 (0.51) | ALDH1A1GAALMNAMAPTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3932914-A1 | ALPHA-CINNAMIDE COMPOUNDS AND COMPOSITIONS AS HDAC8 INHIBITORS | Valo Health, Inc. (US) | 2022-01-05 | — | — | EP | disclosed |