Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 10/20 | 0.36 |
| ▸ | CDC25B | P30305 | 8/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 6/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | TACR2 | P21452 | 1/20 | 0.33 |
| ▸ | GJB2 | P29033 | 1/20 | 0.33 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.33 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21078687 | 0.93 | HTR1A (0.40) | PDE2AHTR1APTPN1CDC25BBCHE | |
| SCHEMBL21046783 | 0.93 | HTR1A (0.40) | PDE2AHTR1APTPN1CDC25BBCHE | |
| SCHEMBL18788248 | 0.91 | PDE2A (0.44) | PDE2AHTR1APTPN1CDC25BBCHE | |
| SCHEMBL21046350 | 0.83 | PDE2A (0.43) | PDE2AHTR1APTPN1CDC25BBCHE | |
| SCHEMBL18788249 | 0.83 | PDE2A (0.49) | PDE2AHTR1APTPN1CDC25BBCHE | |
| SCHEMBL18788241 | 0.81 | PDE2A (0.42) | PDE2AHTR1APTPN1CDC25BBCHE | |
| SCHEMBL17106843 | 0.81 | HTR1A (0.41) | PDE2AHTR1APTPN1CDC25BBCHE | |
| SCHEMBL17106842 | 0.81 | HTR1A (0.41) | PDE2AHTR1APTPN1CDC25BBCHE | |
| SCHEMBL13648874 | 0.81 | PDE2A (0.44) | PDE2AHTR1APTPN1CDC25BBCHE | |
| SCHEMBL12253797 | 0.80 | PDE2A (0.33) | PDE2AHTR1ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3932931-A1 | A NEBULIZER COMPRISING A PHARMACEUTICAL COMPOSITION COMPRISING 2'- SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | Gilead Sciences, Inc. (US) | 2022-01-05 | — | — | EP | disclosed |