Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 20/20 | 0.56 |
| ▸ | TLR8 | Q9NR97 | 20/20 | 0.56 |
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34464476 | 0.90 | TLR9 (0.51) | TLR9TLR8TLR7 | |
| SCHEMBL24161368 | 0.90 | TLR9 (0.59) | TLR9TLR8TLR7 | |
| SCHEMBL34464477 | 0.90 | TLR9 (0.51) | TLR9TLR8TLR7 | |
| SCHEMBL24161096 | 0.90 | TLR9 (0.51) | TLR9TLR8TLR7 | |
| SCHEMBL24161060 | 0.89 | TLR9 (0.45) | TLR9TLR8TLR7 | |
| SCHEMBL24161106 | 0.88 | TLR9 (0.45) | TLR9TLR8TLR7 | |
| SCHEMBL24161022 | 0.87 | TLR9 (0.43) | TLR9TLR8TLR7 | |
| SCHEMBL24161067 | 0.86 | TLR9 (0.54) | TLR9TLR8TLR7 | |
| SCHEMBL24161262 | 0.84 | TLR9 (0.49) | TLR9TLR8TLR7 | |
| SCHEMBL24161102 | 0.84 | TLR9 (0.54) | TLR9TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3870583-B1 | SUBSTITUTED INDOLE AND INDAZOLE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2026-04-22 | — | — | EP | claimed |
| US-12172995-B2 | Substituted indole and indazole compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-12-24 | — | — | US | claimed |
| US-20210403468-A1 | SUBSTITUTED INDOLE AND INDAZOLE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2021-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12172995-B2 | Substituted indole and indazole compounds | TLR1, TLR7, IDO1 | TLR9 6/4885TLR8 7/4885TLR7 2/4885 |
| US-20210403468-A1 | SUBSTITUTED INDOLE AND INDAZOLE COMPOUNDS | TLR1, TLR7, IDO1 | TLR9 6/4885TLR8 7/4885TLR7 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.