Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 5/20 | 0.41 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.37 |
| ▸ | FURIN | P09958 | 2/20 | 0.37 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | NPY4R | P50391 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24649258 | 0.93 | FAP (0.43) | FAPMAP1LC3BFURINSIRT5HTT | |
| SCHEMBL24477318 | 0.93 | FAP (0.43) | FAPMAP1LC3BFURINSIRT5HTT | |
| SCHEMBL24916540 | 0.93 | FAP (0.43) | FAPMAP1LC3BFURINSIRT5HTT | |
| SCHEMBL24648786 | 0.93 | FAP (0.43) | FAPMAP1LC3BFURINSIRT5HTT | |
| SCHEMBL23347053 | 0.93 | FAP (0.43) | FAPMAP1LC3BFURINSIRT5HTT | |
| SCHEMBL23867876 | 0.93 | FAP (0.43) | FAPMAP1LC3BFURINSIRT5HTT | |
| SCHEMBL23943282 | 0.93 | FAP (0.40) | FAPMAP1LC3BFURINHTTSIRT2 | |
| SCHEMBL25450085 | 0.93 | FAP (0.40) | FAPMAP1LC3BFURINHTTSIRT2 | |
| SCHEMBL24224636 | 0.93 | FAP (0.40) | FAPMAP1LC3BFURINHTTSIRT2 | |
| SCHEMBL24916473 | 0.93 | FURIN (0.42) | FAPMAP1LC3BFURINHTTSIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022006340-A1 | ALK5 INHIBITORS, CONJUGATES, AND USES THEREOF | SILVERBACK THERAPEUTICS, INC. (US) | 2022-01-06 | — | — | WO | disclosed |