Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.45 |
| ▸ | DGKA | P23743 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 3/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24164504 | 1.00 | DNM1 (0.45) | DNM1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL24372391 | 1.00 | DNM1 (0.45) | DNM1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL22642651 | 1.00 | DNM1 (0.45) | DNM1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL24163825 | 0.99 | DNM1 (0.44) | DNM1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL24164558 | 0.99 | DNM1 (0.44) | DNM1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL24164509 | 0.98 | DNM1 (0.43) | DNM1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL24164593 | 0.98 | DNM1 (0.45) | DNM1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL24163828 | 0.96 | DNM1 (0.43) | DNM1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL24164318 | 0.95 | DNM1 (0.45) | DNM1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL24164524 | 0.95 | DNM1 (0.45) | DNM1DGKAPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3350157-B1 | COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS | MODERNATX INC (US) | 2022-01-05 | — | — | EP | disclosed |