Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.55 |
| ▸ | CSF1R | P07333 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24165014 | 1.00 | EGFR (0.55) | EGFRCSF1RPIM1PIM2CNR2 | |
| SCHEMBL25394855 | 0.77 | EGFR (0.74) | EGFRCSF1RMAPTMEN1ALDH1A1 | |
| SCHEMBL25394740 | 0.73 | MAPT (0.75) | EGFRCSF1RMAPTMEN1ALDH1A1 | |
| SCHEMBL9141810 | 0.73 | DRD4 (0.54) | ALDH1A1KMT2A | |
| SCHEMBL9140781 | 0.69 | SLC6A12 (0.58) | MEN1KMT2A | |
| SCHEMBL9140774 | 0.69 | KMT2A (0.59) | MEN1ALDH1A1KMT2A | |
| SCHEMBL29385390 | 0.68 | TNF (0.71) | — | |
| SCHEMBL24164971 | 0.68 | TNF (0.71) | — | |
| SCHEMBL24164969 | 0.68 | TNF (0.71) | — | |
| SCHEMBL30526900 | 0.68 | TNF (0.71) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022005494-A1 | QUINOLINE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALTS, AND METHODS OF USE THEREOF | VTV THERAPEUTICS LLC (US) | 2022-01-06 | — | — | WO | disclosed |