SCHEMBL2416615

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2418124	0.88	APP (0.47)	APPCNR2CNR1NPC1RAB9A
	SCHEMBL2414177	0.87	APP (0.54)	APPCNR2CNR1NPC1RAB9A
	SCHEMBL2433879	0.82	ABCB1 (0.53)	APPCNR2CNR1NPC1RAB9A
	SCHEMBL2413783	0.81	APP (0.54)	APPCNR2CNR1NPC1RAB9A
	SCHEMBL2409162	0.81	APP (0.48)	APPCNR2CNR1NPC1RAB9A
	SCHEMBL23167115	0.81	APP (0.50)	APPCNR2CNR1NPC1RAB9A
	SCHEMBL14478707	0.79	APP (0.54)	APPCNR2CNR1NPC1RAB9A
	SCHEMBL12284212	0.77	APP (0.53)	APPCNR2CNR1NPC1RAB9A
	SCHEMBL23167073	0.74	APP (0.53)	APPNPC1RAB9AMAOBIDO1
	SCHEMBL2415179	0.74	APP (0.53)	APPNPC1RAB9AMAOBIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.