SCHEMBL2416629

SCHEMBL2416629

CC(=O)OC(=O)c1ccccc1C

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.49
RAB9A P51151 2/20 0.49
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
ESR1 P03372 1/20 0.46
ESR2 Q92731 1/20 0.46
HPGD P15428 2/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TSHR P16473 1/20 0.45
MAPT P10636 2/20 0.45
LMNA P02545 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.44
PLK1 P53350 1/20 0.44
PLK2 Q9NYY3 1/20 0.44
CASP3 P42574 1/20 0.44
SENP8 Q96LD8 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP6 Q9GZR1 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL29018015 0.93 NPC1 (0.44) NPC1RAB9AMEN1KMT2AESR1
SCHEMBL777261 0.89 NPC1 (0.53) NPC1RAB9AMEN1KMT2AESR1
SCHEMBL29436920 0.89 NPC1 (0.53) NPC1RAB9AMEN1KMT2AESR1
SCHEMBL2778 0.87 TSHR (0.52) NPC1ESR1HPGDKDM4EALDH1A1
SCHEMBL30084385 0.87 TSHR (0.52) NPC1ESR1HPGDKDM4EALDH1A1
SCHEMBL11586441 0.86 NPC1 (0.47) NPC1RAB9AMEN1KMT2AESR1
SCHEMBL29201681 0.85 NPC1 (0.50) NPC1RAB9AMEN1KMT2AESR1
SCHEMBL10004127 0.85 NPC1 (0.50) NPC1RAB9AMEN1KMT2AESR1
SCHEMBL1896602 0.85 TSHR (0.50) NPC1ESR1HPGDKDM4EALDH1A1
SCHEMBL6383298 0.85 TSHR (0.50) NPC1ESR1HPGDKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117088774-A Efficient synthesis method of methyl o-methylbenzoyl formate 辽宁众辉生物科技有限公司 2023-11-21 CN claimed
US-11069856-B2 Solution for organic EL, method of producing organic EL device and organic EL device JOLED INC. (JP) 2021-07-20 US claimed
CN-115356873-B Resin composition, light-shielding film, method for producing light-shielding film, and substrate with barrier ribs 东丽株式会社 2025-04-25 CN disclosed
WO-2024175295-A1 DETERGENTS AND CLEANING AGENTS COMPRISING DISPERSIN AND FRAGRANCE HENKEL AG & CO. KGAA (DE) 2024-08-29 WO disclosed
CN-111333560-B Method for preparing spiro beta-lactam 合肥工业大学 2024-01-23 CN disclosed
CN-117088774-A Efficient synthesis method of methyl o-methylbenzoyl formate 辽宁众辉生物科技有限公司 2023-11-21 CN disclosed
CN-117088774-A Efficient synthesis method of methyl o-methylbenzoyl formate 辽宁众辉生物科技有限公司 2023-11-21 CN disclosed
CN-218784812-U Synthesizer of o-methyl benzoyl chloride 抚顺友联科技有限公司 2023-04-04 CN disclosed
CN-114478241-A Preparation method of arylformyl formic ether 山东京博生物科技有限公司 2022-05-13 CN disclosed
CN-108350351-B Composition for organic photoelectric element, and display device 三星SDI株式会社 2020-09-15 CN disclosed
CN-111393291-A Novel synthesis method of α -carbonyl acid ester 宁波海曙琼杰化工技术研发工作室 2020-07-10 CN disclosed
US-8288462-B2 Polyolefin resin composition ADEKA CORPORATION (JP) 2012-10-16 US disclosed
US-20110218279-A1 POLYOLEFIN RESIN COMPOSITION ADEKA CORPORATION (JP) 2011-09-08 US disclosed
US-7875283-B2 A stent coated with hydrophobic polymer having water-labile bonds and strength to withstand forces of the vascular systems and also biodegrades on its surface rather than bulk erosion; mechanical properties; drug delivery; a polyester,-anhydride or -amide having the monomer, trimellitylimidotyrosine ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2011-01-25 US disclosed
US-7576245-B2 Fluorous tagging and scavenging reactants and methods of synthesis and use thereof FLUOROUS TECHNOLOGIES INCORPORATED (US) 2009-08-18 US disclosed
US-3947488-A O-Acylation using organothallium compounds TAYLOR EDWARD C 1976-03-30 US disclosed