SCHEMBL2778

SCHEMBL2778

CC(=O)OC(=O)c1ccccc1C(=O)OC(C)=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.52
ITGB1 P05556 1/20 0.49
ITGA5 P08648 1/20 0.49
ALDH1A1 P00352 7/20 0.48
HSD17B10 Q99714 4/20 0.47
KDM4E B2RXH2 3/20 0.47
TDP1 Q9NUW8 3/20 0.47
ESR1 P03372 1/20 0.47
ITGB3 P05106 1/20 0.47
ITGA2B P08514 1/20 0.47
HMGB1 P09429 1/20 0.47
HPGD P15428 1/20 0.47
GGT1 P19440 1/20 0.47
PTGS1 P23219 1/20 0.47
PTGS2 P35354 1/20 0.47
BLM P54132 1/20 0.47
NAPRT Q6XQN6 1/20 0.47
LMNA P02545 3/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30084385 1.00 TSHR (0.52) TSHRITGB1ITGA5ALDH1A1HSD17B10
SCHEMBL6383298 0.98 TSHR (0.50) TSHRITGB1ITGA5ALDH1A1HSD17B10
SCHEMBL1896602 0.98 TSHR (0.50) TSHRITGB1ITGA5ALDH1A1HSD17B10
Acetone SCHEMBL29281281 0.98 TSHR (0.50) TSHRITGB1ITGA5ALDH1A1HSD17B10
Acetic Acid SCHEMBL28536661 0.95 TSHR (0.48) TSHRITGB1ITGA5ALDH1A1HSD17B10
SCHEMBL5006514 0.93 TSHR (0.47) TSHRITGB1ITGA5ALDH1A1HSD17B10
SCHEMBL154741 0.91 ALDH1A1 (0.58) TSHRITGB1ITGA5ALDH1A1HSD17B10
Phosphoric Acid SCHEMBL28487093 0.91 TSHR (0.46) TSHRITGB1ITGA5ALDH1A1HSD17B10
SCHEMBL18688239 0.89 TSHR (0.44) TSHRITGB1ITGA5ALDH1A1HSD17B10
Acetic Acid SCHEMBL28815277 0.89 ALDH1A1 (0.56) TSHRITGB1ITGA5ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 93012 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260115191-A1 Nilotinib Compositions with Enhanced Solubility NEOFORM BIOPHARMACEUTICAL LTD (CN) 2026-04-30 US claimed
US-12599610-B2 Solid dosage formulations of an orexin receptor antagonist MERCK SHARP & DOHME LLC (US) 2026-04-14 US claimed
US-20260096994-A1 SOLID DISPERSIONS HAVING STABILIZED EMULSION PARTICLES BOEHRINGER INGELHEIM INT (DE) 2026-04-09 US claimed
US-12582629-B1 Extended-release pharmaceutical compositions of Ralinepag INNOVATE THERAPEUTICS LLC (US) 2026-03-24 US claimed
US-20260069544-A1 CENTANAFADINE MULTIPHASIC CONTROLLED-RELEASE PHARMACEUTICAL FORMULATION INNOVATE THERAPEUTICS LLC (US) 2026-03-12 US claimed
US-20260062394-A1 PROCESSES FOR PREPARING OXAZOLIDINONE COMPOUNDS MERCK SHARP & DOHME LLC (US) 2026-03-05 US claimed
EP-4680227-A1 FORMULATIONS OF DANICOPAN AND METHODS OF USE THEREOF Alexion Pharmaceuticals, Inc. (US) 2026-01-21 EP claimed
WO-2025261803-A1 NOVEL GABA-PRODUCING LEVILACTOBACILLUS BREVIS STRAIN AND ITS USE EVONIK OPERATIONS GMBH (DE) 2025-12-26 WO claimed
US-12502358-B1 Centanafadine multiphasic controlled-release pharmaceutical formulation INNOVATE THERAPEUTICS LLC (US) 2025-12-23 US claimed
US-20250375418-A1 1-(NAPHTHALEN-2-YL)-3-AZABICYCLO[3.1.0]HEXANE FOR TREATING MAJOR DEPRESSIVE DISORDER OTSUKA PHARMA CO LTD (JP) 2025-12-11 US claimed
US-3997346-A Method for stabilizing the image of a thermally developable photosensitive material FUJI PHOTO FILM CO., LTD. (JA) 1976-12-14 US claimed
US-3981984-A Color film coating of tablets and the like COLORCON INCORPORATED (US) 1976-09-21 US claimed
US-3965260-A Anti-inflammatory dipeptide McArthur, John N. (CA) 1976-06-22 US claimed
US-3961041-A PARKINSON'S DISEASE INTERX RESEARCH CORPORATION (US) 1976-06-01 US claimed
US-3957523-A CELLULOSE DERIVATIVES SHINETSU CHEMICAL COMPANY (JA) 1976-05-18 US claimed
US-3953360-A DISPERSION OF ACTIVATED CHARCOAL IN POLYMER MATRIX TOYO JOZO COMPANY, LTD. (JA) 1976-04-27 US claimed
US-3951859-A Molecular sieving particle and preparation thereof TOYO JOZO CO., LTD. (JA) 1976-04-20 US claimed
US-3943063-A Preparation of microcapsules TOYO JOZO COMPANY, LTD. (JA) 1976-03-09 US claimed
US-3937798-A METHOD OF CONTROLLING HYDROGEN ION CONCENTRATION BY MICROCAPSULES FUJI PHOTO FILM CO., LTD. (JA) 1976-02-10 US claimed
US-3933508-A ORGANIC SILVER SALT, SILVER HALIDE, REDUCING AGENT, BINDER FUJI PHOTO FILM CO., LTD. (JA) 1976-01-20 US claimed