Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7279522 | 0.90 | CTSL (0.46) | CTSLCTSBCTSKTSHRAGTR2 | |
| SCHEMBL17043033 | 0.90 | CTSL (0.50) | CTSLCTSBCTSKTSHRAGTR2 | |
| SCHEMBL17043168 | 0.90 | CTSL (0.50) | CTSLCTSBCTSKTSHRAGTR2 | |
| SCHEMBL17043034 | 0.90 | CTSL (0.50) | CTSLCTSBCTSKTSHRAGTR2 | |
| SCHEMBL598878 | 0.88 | TSHR (0.50) | CTSLCTSBCTSKTSHRAGTR2 | |
| SCHEMBL477464 | 0.88 | TSHR (0.50) | CTSLCTSBCTSKTSHRAGTR2 | |
| SCHEMBL477463 | 0.88 | TSHR (0.50) | CTSLCTSBCTSKTSHRAGTR2 | |
| SCHEMBL13095848 | 0.84 | CTSL (0.41) | CTSLCTSBCTSKTSHRAGTR2 | |
| SCHEMBL1928095 | 0.84 | TSHR (0.58) | CTSLCTSBCTSKTSHRNAAA | |
| SCHEMBL17019782 | 0.84 | TSHR (0.58) | CTSLCTSBCTSKTSHRNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3707151-B1 | STING MODULATOR COMPOUNDS, AND METHODS OF MAKING AND USING | TAKEDA PHARMACEUTICALS CO (JP) | 2022-01-05 | — | — | EP | disclosed |