Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24166791 | 1.00 | LRRK2 (0.33) | LRRK2FKBP1ACYP3A4KDM4E | |
| SCHEMBL783056 | 1.00 | LRRK2 (0.33) | LRRK2FKBP1ACYP3A4KDM4E | |
| SCHEMBL30106058 | 1.00 | LRRK2 (0.33) | LRRK2FKBP1ACYP3A4KDM4E | |
| SCHEMBL13866332 | 0.89 | FKBP1A (0.33) | LRRK2FKBP1A | |
| SCHEMBL18669498 | 0.89 | FKBP1A (0.33) | LRRK2FKBP1A | |
| SCHEMBL13866331 | 0.89 | FKBP1A (0.33) | LRRK2FKBP1A | |
| SCHEMBL11970909 | 0.87 | FKBP1A (0.31) | FKBP1A | |
| SCHEMBL13866303 | 0.83 | — | — | |
| SCHEMBL20572720 | 0.83 | — | — | |
| SCHEMBL28660515 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3707151-B1 | STING MODULATOR COMPOUNDS, AND METHODS OF MAKING AND USING | TAKEDA PHARMACEUTICALS CO (JP) | 2022-01-05 | — | — | EP | disclosed |