Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21933121 | 0.80 | ADRA2A (0.41) | MAP3K14ADRA2A | |
| SCHEMBL13630579 | 0.80 | ADRA2A (0.41) | MAP3K14ADRA2A | |
| SCHEMBL13616553 | 0.80 | ADRA2A (0.41) | MAP3K14ADRA2A | |
| SCHEMBL24593571 | 0.79 | ADRA2A (0.50) | MAP3K14CA1CA2ADRA2A | |
| SCHEMBL12828517 | 0.79 | ADRA2A (0.50) | MAP3K14CA1CA2ADRA2A | |
| SCHEMBL27728300 | 0.79 | MAP3K14 (0.65) | MAP3K14CA2SRD5A1ADRA2A | |
| SCHEMBL24866897 | 0.79 | MAP3K14 (0.65) | MAP3K14ADRA2AADRA2B | |
| SCHEMBL24866905 | 0.79 | MAP3K14 (0.65) | MAP3K14ADRA2AADRA2B | |
| SCHEMBL19889279 | 0.79 | ADRA2A (0.50) | MAP3K14CA1CA2ADRA2A | |
| SCHEMBL12651543 | 0.79 | ADRA2A (0.50) | MAP3K14CA1CA2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3193601-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2022-01-05 | — | — | EP | disclosed |