Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 15/20 | 0.49 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.39 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.39 |
| ▸ | CCNK | O75909 | 1/20 | 0.39 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22269153 | 0.89 | MAPK14 (0.43) | MAPK14KCNJ5KCNJ3CCNKCDK12 | |
| SCHEMBL22269149 | 0.89 | MAPK14 (0.43) | MAPK14KCNJ5KCNJ3CCNKCDK12 | |
| SCHEMBL13463048 | 0.82 | MAPK14 (0.52) | MAPK14CA2 | |
| SCHEMBL16447323 | 0.81 | MAPK14 (0.50) | MAPK14CCNKCDK12CA2 | |
| SCHEMBL15077466 | 0.81 | MAPK14 (0.50) | MAPK14CCNKCDK12CA2 | |
| SCHEMBL22705180 | 0.80 | CA2 (0.42) | MAPK14KCNJ5KCNJ3CCNKCDK12 | |
| SCHEMBL16447426 | 0.80 | MAPK14 (0.46) | MAPK14CA2 | |
| SCHEMBL15078725 | 0.80 | MAPK14 (0.46) | MAPK14CCNKCDK12 | |
| SCHEMBL15077467 | 0.80 | MAPK14 (0.46) | MAPK14CA2 | |
| SCHEMBL1586695 | 0.80 | MAPK14 (0.43) | MAPK14KCNJ5KCNJ3CCNKCDK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3030519-B1 | TRICYCLIC BENZOXABOROLE COMPOUNDS AND USES THEREOF | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2022-01-05 | — | — | EP | disclosed |