SCHEMBL24170296

SCHEMBL24170296

C/C=C/C1CCC(C2CCC(COc3ccc(OCC4CC4)c(F)c3F)CC2)CC1

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 5/20 0.36
HTR2A P28223 4/20 0.36
HTR2B P41595 4/20 0.36
RIPK1 Q13546 1/20 0.35
PDE4B Q07343 5/20 0.33
PDE4A P27815 1/20 0.33
PDE4C Q08493 1/20 0.33
PDE4D Q08499 1/20 0.33
SLC6A9 P48067 1/20 0.32
BRD4 O60885 2/20 0.32
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22820269 0.96 HTR2A (0.34) HTR2CHTR2AHTR2BRIPK1PDE4B
SCHEMBL13417731 0.96 HTR2A (0.34) HTR2CHTR2AHTR2BRIPK1PDE4B
SCHEMBL18509559 0.95 PDE4B (0.37) HTR2CHTR2AHTR2BPDE4BPDE4A
SCHEMBL16807233 0.94 HTR2A (0.33) HTR2CHTR2AHTR2BRIPK1PDE4B
SCHEMBL13417689 0.94 HTR2A (0.33) HTR2CHTR2AHTR2BRIPK1PDE4B
SCHEMBL17461521 0.92 HTR2C (0.32) HTR2CHTR2AHTR2BRIPK1PDE4B
SCHEMBL9924977 0.92 HTR2A (0.34) HTR2CHTR2AHTR2BRIPK1
SCHEMBL15723121 0.92 HTR2A (0.32) HTR2CHTR2AHTR2BRIPK1HPGD
SCHEMBL14391382 0.92 PDE4B (0.35) HTR2CHTR2AHTR2BRIPK1PDE4B
SCHEMBL22820268 0.91 HTR2A (0.36) HTR2CHTR2AHTR2BRIPK1PDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230295511-A1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2023-09-21 US disclosed
US-20230295511-A1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2023-09-21 US disclosed
WO-2022003001-A1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2022-01-06 WO disclosed