Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13417689 | 1.00 | HTR2A (0.33) | HTR2AHTR2CHTR2BRIPK1PDE4B | |
| SCHEMBL13417687 | 0.96 | HTR2A (0.34) | HTR2AHTR2CHTR2BRIPK1PDE4B | |
| SCHEMBL24170296 | 0.94 | HTR2C (0.36) | HTR2AHTR2CHTR2BRIPK1PDE4B | |
| SCHEMBL22820269 | 0.90 | HTR2A (0.34) | HTR2AHTR2CHTR2BRIPK1PDE4B | |
| SCHEMBL13417731 | 0.90 | HTR2A (0.34) | HTR2AHTR2CHTR2BRIPK1PDE4B | |
| SCHEMBL18509559 | 0.89 | PDE4B (0.37) | HTR2AHTR2CHTR2BPDE4BPDE4A | |
| SCHEMBL26277379 | 0.88 | HTR2A (0.39) | HTR2AHTR2CHTR2BRIPK1PDE4B | |
| SCHEMBL15316645 | 0.87 | RIPK1 (0.33) | HTR2AHTR2CHTR2BRIPK1PDE4B | |
| SCHEMBL15723121 | 0.86 | HTR2A (0.32) | HTR2AHTR2CHTR2BRIPK1HPGD | |
| SCHEMBL14391382 | 0.86 | PDE4B (0.35) | HTR2AHTR2CHTR2BRIPK1PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11873438-B2 | Liquid-crystal medium | MERCK PATENT GMBH (DE) | 2024-01-16 | — | — | US | disclosed |
| US-20230295511-A1 | LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2023-09-21 | — | — | US | disclosed |
| US-20180171231-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-06-21 | — | — | US | disclosed |
| US-20180046033-A1 | LIQUID CRYSTAL DISPLAY AND LIQUID CRYSTAL COMPOSITION COMPRISED THEREOF | SAMSUNG DISPLAY CO., LTD. (KR) | 2018-02-15 | — | — | US | disclosed |
| US-20180002604-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-01-04 | — | — | US | disclosed |
| US-20170362506-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2017-12-21 | — | — | US | disclosed |
| US-9714381-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-07-25 | — | — | US | disclosed |
| US-20170044436-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2017-02-16 | — | — | US | disclosed |
| US-20160208170-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2016-07-21 | — | — | US | disclosed |
| US-20160046863-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2016-02-18 | — | — | US | disclosed |
| US-20150166890-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-06-18 | — | — | US | disclosed |
| US-7670504-B2 | Nematic liquid crystal composition and liquid crystal display device using the same | DAINIPPON INK & CHEMICALS, INC. (JP) | 2010-03-02 | — | — | US | disclosed |
| US-7651630-B2 | Difluorobenzene derivative and nematic liquid crystal composition using the same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2010-01-26 | — | — | US | disclosed |
| US-20090050843-A1 | DIFLUOROBENZENE DERIVATIVE AND NEMATIC LIQUID CRYSTAL COMPOSITION USING THE SAME | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2009-02-26 | — | — | US | disclosed |
| US-20080111107-A1 | Nematic Liquid Crystal Composition And Liquid Crystal Display Device Using The Same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2008-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090050843-A1 | DIFLUOROBENZENE DERIVATIVE AND NEMATIC LIQUID CRYSTAL COMPOSITION USING THE SAME | HCN2, TRPV2, TRPV5 | HTR2A 3728/4885HTR2C 3149/4885HTR2B 3198/4885 |
| US-20160208170-A1 | LIQUID-CRYSTALLINE MEDIUM | NEFM, VIM, PLG | HTR2A 755/4885HTR2C 523/4885HTR2B 1141/4885 |
| US-20080111107-A1 | Nematic Liquid Crystal Composition And Liquid Crystal Display Device Using The Same | PIEZO1, KIF20B, VCL | HTR2A 1878/4885HTR2C 2306/4885HTR2B 487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.