SCHEMBL2417039

SCHEMBL2417039

O=C(NC(Cc1c[nH]c2ccccc12)C(=O)NCCNC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)OCc1ccccc1)OCc1ccccc1

nearest known ligand 0.90

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NMBR P28336 11/20 0.90
MAPT P10636 2/20 0.79
GAA P10253 1/20 0.79
HTT P42858 1/20 0.79
LMNA P02545 1/20 0.76
CA2 P00918 1/20 0.74
BMP1 P13497 1/20 0.69
MMP9 P14780 1/20 0.68
MMP8 P22894 1/20 0.68
TACR1 P25103 1/20 0.67
BRS3 P32247 2/20 0.64
TACR3 P29371 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2415823 0.96 NMBR (0.87) NMBRMAPTGAAHTTLMNA
SCHEMBL2379686 0.96 NMBR (0.87) NMBRMAPTGAAHTTLMNA
SCHEMBL2420021 0.95 NMBR (0.85) NMBRMAPTGAAHTTLMNA
SCHEMBL15145380 0.95 NMBR (0.85) NMBRMAPTGAAHTTLMNA
SCHEMBL2382050 0.95 NMBR (0.85) NMBRMAPTGAAHTTLMNA
SCHEMBL2421029 0.95 NMBR (0.85) NMBRMAPTGAAHTTLMNA
SCHEMBL2370248 0.95 NMBR (0.85) NMBRMAPTGAAHTTLMNA
SCHEMBL2417077 0.95 NMBR (0.85) NMBRMAPTGAAHTTLMNA
SCHEMBL2382811 0.95 NMBR (0.85) NMBRMAPTGAAHTTLMNA
SCHEMBL2370414 0.95 NMBR (0.85) NMBRMAPTGAAHTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2365052-B1 pH tuneable-gellant for use in consumer product compositions PROCTER & GAMBLE (US) 2016-07-13 EP claimed
US-20110224124-A1 pH Tuneable Amido-Gellant For Use In Consumer Product Compositions THE PROCTER & GAMBLE COMPANY 2011-09-15 US claimed
EP-2365052-A1 pH tuneable-gellant for use in consumer product compositions The Procter & Gamble Company (US) 2011-09-14 EP claimed
EP-2365052-A1 pH tuneable-gellant for use in consumer product compositions The Procter & Gamble Company (US) 2011-09-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224124-A1 pH Tuneable Amido-Gellant For Use In Consumer Product Compositions AGPAT2, AGPAT5, GNAO1 NMBR 401/4885MAPT 1301/4885GAA 349/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.