Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 7/20 | 0.44 |
| ▸ | ACVR2A | P27037 | 2/20 | 0.42 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | LOX | P28300 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24171871 | 0.81 | FYN (0.59) | FYNDYRK1ACHEK2TGFBR1CHEK1 | |
| SCHEMBL24171393 | 0.79 | FYN (0.47) | FYNCHEK2TGFBR1 | |
| SCHEMBL11262307 | 0.74 | CYP2A6 (0.44) | — | |
| SCHEMBL16116782 | 0.73 | LOX (0.55) | ACVR2ATGFBR2LRRK2DYRK1ATGFBR1 | |
| SCHEMBL30626327 | 0.73 | LOX (0.55) | ACVR2ATGFBR2LRRK2DYRK1ATGFBR1 | |
| SCHEMBL30042310 | 0.73 | DYRK1A (0.49) | ACVR2ATGFBR2LRRK2DYRK1APIK3CA | |
| SCHEMBL94462 | 0.73 | DYRK1A (0.49) | ACVR2ATGFBR2LRRK2DYRK1APIK3CA | |
| SCHEMBL30042175 | 0.73 | CYP2A6 (0.57) | FYNACVR2ATGFBR2DYRK1APIK3CA | |
| SCHEMBL155546 | 0.73 | DYRK1A (0.46) | ACVR2ATGFBR2LRRK2DYRK1ATGFBR1 | |
| SCHEMBL18481804 | 0.72 | LOX (0.47) | ACVR2ATGFBR2LRRK2DYRK1ATGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220002277-A1 | PYRIDONE DERIVATIVE HAVING TETRAHYDROPYRANYLMETHYL GROUP | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2022-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220002277-A1 | PYRIDONE DERIVATIVE HAVING TETRAHYDROPYRANYLMETHYL GROUP | AXL, TYRO3, LCK | FYN 6/4885ACVR2A 491/4885TGFBR2 545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.