Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 8/20 | 0.59 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.57 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.57 |
| ▸ | KIT | P10721 | 5/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.51 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15334401 | 0.87 | FYN (0.76) | FYNCHEK2CHEK1TGFBR1 | |
| SCHEMBL29576661 | 0.87 | FYN (0.76) | FYNCHEK2CHEK1TGFBR1 | |
| SCHEMBL24171393 | 0.81 | FYN (0.47) | FYNCHEK2KITTGFBR1NTRK1 | |
| SCHEMBL24171148 | 0.81 | FYN (0.44) | FYNCHEK2CHEK1TGFBR1DYRK1A | |
| SCHEMBL15334358 | 0.79 | FYN (0.61) | FYNCHEK2CHEK1TGFBR1 | |
| SCHEMBL22703879 | 0.79 | FYN (0.67) | FYNCHEK2CHEK1TGFBR1 | |
| SCHEMBL28881764 | 0.79 | FYN (0.61) | FYNCHEK2CHEK1TGFBR1 | |
| SCHEMBL29631684 | 0.79 | FYN (0.61) | FYNCHEK2CHEK1TGFBR1 | |
| SCHEMBL23158777 | 0.79 | PDGFRB (0.59) | FYNCHEK2CHEK1KITPDGFRB | |
| SCHEMBL7140279 | 0.78 | ALDH1A1 (0.59) | FYNKITPDGFRBPDGFRAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220002277-A1 | PYRIDONE DERIVATIVE HAVING TETRAHYDROPYRANYLMETHYL GROUP | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2022-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220002277-A1 | PYRIDONE DERIVATIVE HAVING TETRAHYDROPYRANYLMETHYL GROUP | AXL, TYRO3, LCK | FYN 6/4885CHEK2 509/4885CHEK1 1346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.