SCHEMBL241747

SCHEMBL241747

c1ccc2c(c1)cnc1c3ccccc3ccc21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 3/20 0.54
KDM4E B2RXH2 1/20 0.54
GPR3 P46089 1/20 0.54
ALDH1A1 P00352 2/20 0.52
HSD17B10 Q99714 2/20 0.52
CYP2A6 P11509 1/20 0.52
TSHR P16473 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
MAPT P10636 3/20 0.46
CYP3A4 P08684 2/20 0.46
LMNA P02545 2/20 0.46
APEX1 P27695 1/20 0.46
MAPK1 P28482 1/20 0.46
PMP22 Q01453 1/20 0.46
HIF1A Q16665 1/20 0.44
CYP1B1 Q16678 1/20 0.44
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3322796 0.98 HPRT1 (0.52) HPRT1KDM4EGPR3ALDH1A1HSD17B10
SCHEMBL30956235 0.96 HPRT1 (0.61) HPRT1KDM4EGPR3ALDH1A1HSD17B10
Perchlorate SCHEMBL3915498 0.89 KDM4E (0.44) HPRT1KDM4EGPR3ALDH1A1HSD17B10
SCHEMBL19748987 0.89 KDM4E (0.60) HPRT1KDM4EGPR3ALDH1A1HSD17B10
SCHEMBL14150896 0.87 KDM4E (0.46) HPRT1KDM4EGPR3ALDH1A1HSD17B10
SCHEMBL2299764 0.86 KDM4E (0.48) HPRT1KDM4EGPR3ALDH1A1HSD17B10
SCHEMBL14150966 0.85 CLK1 (0.51) HPRT1KDM4EGPR3ALDH1A1HSD17B10
SCHEMBL13845107 0.84 CYP2A6 (0.47) HPRT1KDM4EGPR3ALDH1A1HSD17B10
SCHEMBL2488607 0.84 KDM4E (0.58) HPRT1KDM4EGPR3ALDH1A1HSD17B10
SCHEMBL18842483 0.83 HPRT1 (0.44) HPRT1KDM4EGPR3ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 344 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117069732-B Preparation method of benzo [ c ] phenanthridine natural product and derivative thereof 沈阳药科大学 2024-04-26 CN claimed
CN-117069732-A Preparation method of benzo [ c ] phenanthridine natural product and derivative thereof 沈阳药科大学 2023-11-17 CN claimed
CN-116444478-A Preparation method and application of aromatic benzo [ c ] phenanthridine alkaloid intermediate compound 宁波九胜创新医药科技有限公司 2023-07-18 CN claimed
CN-114716405-A Preparation method and application of aromatic benzo [ c ] phenanthridine alkaloid intermediate compound 宁波九胜创新医药科技有限公司 2022-07-08 CN claimed
US-20210139610-A1 COMPOSITIONS AND METHODS FOR MEDIATING EPS RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (US) 2021-05-13 US claimed
EP-3813811-A2 COMPOSITIONS AND METHODS FOR MEDIATING EPS Research Institute at Nationwide Children's Hospital (US) 2021-05-05 EP claimed
US-20150216174-A1 POTENTIATING AGENTS FOR PROTECTING PLANTS FROM FUNGAL INFECTIONS GREEN IMPULSE SAS (FR) 2015-08-06 US claimed
EP-2871964-A1 POTENTIATING AGENTS FOR PROTECTING PLANTS FROM FUNGAL INFECTIONS Université d'Angers (FR) 2015-05-20 EP claimed
WO-2014012766-A1 POTENTIATING AGENTS FOR PROTECTING PLANTS FROM FUNGAL INFECTIONS Université d'Angers (FR) 2014-01-23 WO claimed
EP-2687097-A1 Potentiating agents for protecting plants from fungal infections UNIVERSITE D'ANGERS (FR) 2014-01-22 EP claimed
WO-2004043363-A2 PROTEIN-STABILIZED LIPOSOMAL FORMULATIONS OF PHARMACEUTICAL AGENTS AZAYA THERAPEUTICS, INC. (US) 2004-05-27 WO claimed
EP-0487930-B1 Benzo[C]phenanthridinium derivatives NIPPON KAYAKU KK (JP) 1999-03-24 EP claimed
EP-0487930-A1 Process for preparing benzo[C]phenanthridinium derivatives, and novel compounds prepared by said process NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1992-06-03 EP claimed
EP-0326628-A1 Method for inhibiting the release of histamine VIPONT PHARMACEUTICAL, INC. (US) 1989-08-09 EP claimed
EP-0326627-A1 Method for inhibiting bone resorption and collagenase release VIPONT PHARMACEUTICAL, INC. (US) 1989-08-09 EP claimed
US-4769452-A Production of purity benzo-c-phenanthridine alkaloid salts VIPONT LABORATORIES, INC. (US) 1988-09-06 US claimed
US-4767861-A Recovery of benzo-c-phenanthridine alkaloids VIPONT LABORATORIES (US) 1988-08-30 US claimed
US-4737503-A BENZOPHENANTHRIDINE ALKALOID VIPONT LABORATORIES, INC. (US) 1988-04-12 US claimed
US-4683133-A PUMPING ALKALOID SALT SOLUTIONS ON GUMS VIPONT LABORATORIES, INC. (US) 1987-07-28 US claimed
US-4590061-A BENZO-C-PHENANTHRIDINE ALKALOIDS VIPONT LABORATORIES, INC. (US) 1986-05-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150216174-A1 POTENTIATING AGENTS FOR PROTECTING PLANTS FROM FUNGAL INFECTIONS ERG28, CTSA, MAN2A1 HPRT1 3460/4885KDM4E 4627/4885GPR3 3479/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.