Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 17/20 | 0.65 |
| ▸ | ACHE | P22303 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21452607 | 0.94 | STING1 (0.64) | STING1ACHE | |
| SCHEMBL21452766 | 0.90 | STING1 (0.57) | STING1ACHE | |
| SCHEMBL21405886 | 0.90 | STING1 (0.79) | STING1ACHE | |
| SCHEMBL21405817 | 0.89 | STING1 (0.83) | STING1ACHE | |
| SCHEMBL24175699 | 0.88 | STING1 (0.62) | STING1ACHE | |
| SCHEMBL21405933 | 0.88 | STING1 (0.62) | STING1ACHE | |
| SCHEMBL21452576 | 0.86 | STING1 (0.64) | STING1ACHE | |
| SCHEMBL23480422 | 0.85 | STING1 (0.64) | STING1ACHE | |
| SCHEMBL24451326 | 0.84 | STING1 (0.67) | STING1ACHE | |
| SCHEMBL24450990 | 0.84 | STING1 (0.67) | STING1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022002077-A1 | ARYL AROMATIC HETEROCYCLIC DERIVATIVE AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海海和药物研究开发股份有限公司 | 2022-01-06 | — | — | WO | disclosed |
| CN-113861161-A | Aryl aromatic heterocyclic derivative and preparation method and application thereof | 上海海和药物研究开发股份有限公司 | 2021-12-31 | — | — | CN | disclosed |