Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22144380 | 1.00 | TSHR (0.42) | TSHRANPEPALDH1A1ALOX15TRPV3 | |
| SCHEMBL17808442 | 0.83 | TSHR (0.48) | TSHRANPEPALDH1A1 | |
| SCHEMBL11595660 | 0.83 | ALDH1A1 (0.41) | TSHRALDH1A1ALOX15TRPV3TRPA1 | |
| SCHEMBL7962706 | 0.82 | TSHR (0.54) | TSHRANPEP | |
| SCHEMBL6025396 | 0.82 | ALDH1A1 (0.34) | TSHRALDH1A1ALOX15TRPV3TRPA1 | |
| SCHEMBL10896616 | 0.81 | ANPEP (0.38) | TSHRANPEPALDH1A1 | |
| SCHEMBL7321740 | 0.81 | — | — | |
| SCHEMBL9407562 | 0.80 | ANPEP (0.43) | TSHRANPEPALDH1A1 | |
| SCHEMBL17919006 | 0.79 | TSHR (0.43) | TSHRANPEPALDH1A1 | |
| SCHEMBL12285467 | 0.79 | TSHR (0.43) | TSHRANPEPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022002102-A1 | QUINAZOLINE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | InventisBio Co., Ltd. (CN) | 2022-01-06 | — | — | WO | disclosed |