Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK7 | P50613 | 10/20 | 0.46 |
| ▸ | CCNH | P51946 | 10/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 7/20 | 0.46 |
| ▸ | CDK9 | P50750 | 7/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.46 |
| ▸ | CDK2 | P24941 | 7/20 | 0.46 |
| ▸ | CCNK | O75909 | 7/20 | 0.46 |
| ▸ | CDK12 | Q9NYV4 | 7/20 | 0.46 |
| ▸ | BRD4 | O60885 | 7/20 | 0.38 |
| ▸ | MNAT1 | P51948 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27162715 | 0.94 | CDK7 (0.45) | CDK7CCNHCCNT1CDK9CCNE1 | |
| SCHEMBL30771942 | 0.94 | CDK7 (0.45) | CDK7CCNHCCNT1CDK9CCNE1 | |
| SCHEMBL24176292 | 0.92 | CDK7 (0.47) | CDK7CCNHCCNT1CDK9CCNE1 | |
| SCHEMBL24176266 | 0.91 | CDK7 (0.47) | CDK7CCNHCCNT1CDK9CCNE1 | |
| SCHEMBL21184613 | 0.91 | CDK7 (0.47) | CDK7CCNHCCNT1CDK9CCNE1 | |
| SCHEMBL21178765 | 0.91 | CDK7 (0.44) | CDK7CCNHCCNT1CDK9CCNE1 | |
| SCHEMBL30771923 | 0.91 | CDK7 (0.44) | CDK7CCNHCCNT1CDK9CCNE1 | |
| SCHEMBL21184440 | 0.91 | CDK7 (0.44) | CDK7CCNHCCNT1CDK9CCNE1 | |
| SCHEMBL27162475 | 0.91 | CDK7 (0.44) | CDK7CCNHCCNT1CDK9CCNE1 | |
| SCHEMBL30771954 | 0.90 | CDK7 (0.45) | CDK7CCNHCCNT1CDK9CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220000890-A1 | INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | MEDIC LIFE SCIENCES, INC. | 2022-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220000890-A1 | INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | CDK7, CDK3, CCNK | CDK7 1/4885CCNH 24/4885CCNT1 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.