Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 6/20 | 1.00 |
| ▸ | PDE2A | O00408 | 2/20 | 0.75 |
| ▸ | PDE6D | O43924 | 2/20 | 0.75 |
| ▸ | PDE8A | O60658 | 2/20 | 0.75 |
| ▸ | PDE5A | O76074 | 2/20 | 0.75 |
| ▸ | PDE9A | O76083 | 2/20 | 0.75 |
| ▸ | PDE8B | O95263 | 2/20 | 0.75 |
| ▸ | PDE6A | P16499 | 2/20 | 0.75 |
| ▸ | PDE6G | P18545 | 2/20 | 0.75 |
| ▸ | PDE4A | P27815 | 2/20 | 0.75 |
| ▸ | PDE6B | P35913 | 2/20 | 0.75 |
| ▸ | PDE6C | P51160 | 2/20 | 0.75 |
| ▸ | PDE1A | P54750 | 2/20 | 0.75 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.75 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.75 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.75 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.75 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.75 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.75 |
| ▸ | PDE6H | Q13956 | 2/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24176321 | 0.89 | ENPP2 (1.00) | ENPP2PDE2APDE6DPDE8APDE5A | |
| SCHEMBL24176468 | 0.85 | ENPP2 (0.76) | ENPP2PDE2APDE6DPDE8APDE5A | |
| SCHEMBL24176473 | 0.84 | ENPP2 (1.00) | ENPP2PDE2APDE6DPDE8APDE5A | |
| SCHEMBL29392391 | 0.80 | HTT (0.67) | ENPP2PDE2APDE6DPDE8APDE5A | |
| SCHEMBL4881700 | 0.80 | HTT (0.67) | ENPP2PDE2APDE6DPDE8APDE5A | |
| SCHEMBL4878644 | 0.79 | ENPP2 (0.66) | ENPP2PDE2APDE6DPDE8APDE5A | |
| SCHEMBL4872832 | 0.73 | ENPP2 (0.58) | ENPP2PDE2APDE6DPDE8APDE5A | |
| SCHEMBL4881992 | 0.72 | TSHR (0.69) | ENPP2PDE2APDE6DPDE8APDE5A | |
| SCHEMBL4879266 | 0.69 | ENPP2 (0.73) | ENPP2KMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL8556169 | 0.69 | DEGS1 (0.69) | KMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022003377-A1 | THIENO[3,4-C]PYRAZOL-3-YL ACETAMIDES AS AUTOTAXIN INHIBITORS | UNI-PHARMA KLEON TSETIS PHARMACEUTICAL LABORATORIES S.A. (GR) | 2022-01-06 | — | — | WO | disclosed |