Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5008045 | 0.85 | HCAR2 (0.52) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL9980510 | 0.80 | GSK3B (0.44) | ALDH1A1GSK3BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6609203 | 0.80 | ALDH1A1 (0.72) | ALDH1A1GSK3BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30664409 | 0.80 | ALDH1A1 (0.72) | ALDH1A1GSK3BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12571419 | 0.79 | ALDH1A1 (0.46) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL21563726 | 0.77 | PTPN1 (0.43) | ALDH1A1GSK3BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23080977 | 0.77 | ALDH1A1 (0.45) | ALDH1A1GSK3BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL892779 | 0.76 | MAPT (0.68) | ALDH1A1GSK3BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10848656 | 0.75 | CDC7 (0.61) | ALDH1A1GSK3BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5392323 | 0.75 | CYP3A4 (0.56) | ALDH1A1GSK3BNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220002796-A1 | QUALITY CONTROL OF LNA OLIGONUCLEOTIDE THERAPEUTICS USING MASSIVELY PARALLEL SEQUENCING | ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) | 2022-01-06 | — | — | US | disclosed |