SCHEMBL24176709

SCHEMBL24176709

Clc1ccc2nc(Nc3ccnnc3)oc2c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR3 Q99500 11/20 0.50
FBP1 P09467 1/20 0.46
PIK3CG P48736 1/20 0.45
S1PR1 P21453 4/20 0.44
RAB9A P51151 2/20 0.43
MAPT P10636 1/20 0.43
PSMB8 P28062 1/20 0.42
PSMB5 P28074 1/20 0.42
BACE1 P56817 1/20 0.42
NPC1 O15118 1/20 0.41
ALDH1A1 P00352 1/20 0.41
GAA P10253 1/20 0.41
PKM P14618 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
PLK4 O00444 1/20 0.41
CHEK1 O14757 1/20 0.41
DAPK3 O43293 1/20 0.41
DYRK3 O43781 1/20 0.41
ROCK2 O75116 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24176375 0.83 NPC1 (0.41) RAB9AMAPTNPC1ALDH1A1GAA
SCHEMBL24176372 0.80 CSNK1D (0.44) RAB9AMAPTNPC1ALDH1A1GAA
SCHEMBL19899602 0.78 S1PR3 (0.50) S1PR3FBP1PIK3CGS1PR1RAB9A
SCHEMBL19899563 0.76 S1PR3 (0.51) S1PR3FBP1PIK3CGS1PR1RAB9A
SCHEMBL3803018 0.75 S1PR3 (0.50) S1PR3FBP1PIK3CGS1PR1RAB9A
SCHEMBL25292085 0.74 SIRT7 (0.53) S1PR3FBP1PIK3CGS1PR1RAB9A
SCHEMBL19899666 0.73 S1PR3 (0.51) S1PR3FBP1PIK3CGS1PR1RAB9A
SCHEMBL17469473 0.72 S1PR3 (0.60) S1PR3FBP1PIK3CGS1PR1RAB9A
SCHEMBL18028787 0.72 S1PR3 (0.60) S1PR3FBP1PIK3CGS1PR1RAB9A
SCHEMBL2135773 0.72 PIK3CG (0.61) S1PR3FBP1PIK3CGS1PR1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022001998-A1 DIARYLAMINE DERIVATIVE USED AS FUNGICIDE 周银平 2022-01-06 WO disclosed